自身免疫疾病正在广泛增加，自身免疫疾病中的生物制品在治疗中起着重要作用。生物制品有吸附特定靶分子和抑制炎症的亲和力。不同的生物制品用于治疗各种自身免疫疾病，通过防止细胞因子解锁细胞并引起炎症。 每种生物制品针对不同的细胞因子。用于治疗自身免疫疾病的常见生物制品分类为i）肿瘤坏死因子-α（TNFα）抑制剂和ii）白细胞介素抑制剂（IL）。除了生物制品，纳米医学已被证明是一种成功的方法，可用于创建具有潜在传递药物到特定器官或组织的药物的定制纳米材料，而不会引起免疫抑制或免疫刺激不良反应。本文回顾了治疗自身免疫疾病（AD）的生物制品及其机制。检查当前开发出的用于治疗自身免疫疾病的创新纳米颗粒治疗法以及其应用于疫苗中。此外，最近的临床试验显示了纳米系统治疗自身免疫疾病的策略。版权所有© Bentham Science Publishers；有任何疑问，请发送电子邮件至epub@benthamscience.net。

Autoimmune disease is increasing widely, and the biologicals in autoimmune disease play a vital role in the cure. Biologicals have an affinity to bind the specific target molecule and suppress inflammation. The different biologicals are used to treat various autoimmune diseases by preventing the cytokines from unlocking cells and causing inflammation. Each biologic targets a different cytokine. The common classes of biologic that are used to treat autoimmune disease are i) Tumor Necrosis Factor-alpha (TNFα) inhibitors and ii) Interleukin Inhibitors (IL). Along with biologics, nanomedicine has shown to be a successful method for creating customized nanomaterials with the potential to deliver medicinal agents to particular organs or tissues drugs without causing immunosuppressive or immunostimulatory adverse effects. This article reviews biologics used in treating Autoimmune Disease (AD) and the mechanism involved. The examination of current developments that have been made to create innovative nanoparticle-based therapies for autoimmune illnesses and their inclusion in vaccines. Also, recent clinical trials display nanosystem strategies for treating AD.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.