头颈部软组织钙化是相对常见的现象，是各种良性和恶性病理学因素的结果。鉴于潜在病因的广泛范围，它们可能会呈现出诊断上的挑战。尿毒症肿瘤性钙化（UTC）是终末期肾脏病（ESRD）罕见的并发症，可导致转移性软组织钙化。常见的部位包括肩膀、肘部和手部的关节周围软组织（Pan和Chen，2016）。UTC也可以影响颈椎并模仿骨肉瘤（Zhou等，2018）。我们介绍了一位71岁的女性病人，她患有高血压、左颈动脉狭窄、二尖瓣脱垂和由2型糖尿病（DMII）引起的腹膜透析的ESRD，并发现她有大量、异质性的双侧钙化颈肿块。根据她的临床史、实验室结果和影像学表现，她被诊断患有UTC。除了这个病例，我们还提供了关于肿瘤性钙化（TC）的概述和头颈部钙化病变的鉴别诊断。版权所有©2023 Elsevier Inc.。保留所有权利。

Soft-tissue calcifications in the head and neck are relatively common and are the result of a wide variety of benign and malignant pathologies. They can present a diagnostic challenge given the broad range of underlying etiologies. Uremic tumoral calcinosis (UTC) is a rare complication of end-stage renal disease (ESRD) resulting from metastatic soft tissue calcification. Common sites include periarticular soft tissues of the shoulders, elbows, and hands (Pan and Chen, 2016). UTC can also affect the cervical spine and mimic osteosarcomas (Zhou et al., 2018). We present the case of a 71-year-old female with hypertension, left carotid artery stenosis, mitral valve prolapse, and ESRD secondary to diabetes mellitus type II (DMII) on peritoneal dialysis who was found to have large, heterogeneous, bilateral calcified neck masses. Given her clinical history, laboratory results, and imaging findings, she was diagnosed with UTC. In addition to this case, we provide an overview of tumoral calcinosis (TC) and a differential diagnosis for calcified lesions of the head and neck.Copyright © 2023 Elsevier Inc. All rights reserved.