Calophyllum属以其酚类成分而闻名，尤其是香豆素，这些物质已被证明具有广泛的显着生物活性。在本研究中，从Calophyllum lanigerum的茎皮中分离出了四种已知的酚类成分和两种三萜类化合物。这些化合物是两种吡喃并色酮酸，分别称为caloteysmannic酸(1)、异碳龙酸(2)、一种简单的二羟基黄酮，即euxanthone(3)、一种香豆素，名为calanone(4)，以及两种常见的三萜类化合物，friedelin(5)和stigmasterol(6)。这是首次报道在Calophyllum属中分离出吡喃并色酮酸。对n-己烷提取物(87.14±2.04μg/mL；81.46±2.42μg/mL)以及吡喃并色酮酸(1[79.96±2.39μM；83.41±3.39μM]和2[57.88±2.34；53.04±3.18μM])对两种癌细胞系MDA-MB-231和MG-63进行了细胞毒性评估。结果显示，所有测试样品均表现出中等细胞毒性。

Genus Calophyllum is well-known for its phenolic constituents, especially coumarins, which have shown to have a wide range of significant biological activities. In this study, four known phenolic constituents and two triterpenoids have been isolated from the stem bark of Calophyllum lanigerum. The compounds were two pyranochromanone acids are known as caloteysmannic acid (1), isocalolongic acid (2), a simple dihydroxyxanthone, namely euxanthone (3), one coumarin named calanone (4), and two common triterpenoids, friedelin (5), and stigmasterol (6). Chromanone acids were reported for the first time in this Calophyllum species. Cytotoxic evaluations were carried out on n-hexane extract (87.14 ± 2.04 µg/mL; 81.46 ± 2.42 µg/mL) followed by the chromanone acids (1 [79.96 ± 2.39 µM; 83.41 ± 3.39 µM] & 2 [57.88 ± 2.34; 53.04 ± 3.18 µM]) against two cancerous cell lines, MDA-MB-231 and MG-63 cell lines, respectively. The results showed that all tested samples exhibited moderate cytotoxicity.