HPV高风险感染和HPV相关癌症的重要负担可以通过接种疫苗得到缓解。本研究旨在调查科威特大学女性学生接受HPV疫苗接种的意愿，并考察其与一般疫苗阴谋论信念（VCBs）的可能关联。本横断面调查研究于2022年9月至11月期间进行，采用经过验证的VCB量表作为调查工具。最终样本包括611名受访者，中位年龄为22岁，大多数为阿拉伯族裔（n = 600, 98.2%）。只有360名受访者（56.9％）在参与之前听说过HPV，这些学生显示出高于平均水平的HPV知识水平（平均知识得分为12.7 ± 2.6，最高得分为16），其中只有33人自报接种过HPV疫苗（9.2％）。接受免费HPV疫苗接种的意愿在参与者中占69.8％，20.1％表示有犹豫，10.1％表示反对。如果需要付费，接受HPV疫苗接种的比例为23.1％。HPV疫苗犹豫/反抗的原因包括对HPV疾病风险的漠不关心，对HPV疫苗的信心不足和不方便。支持VCBs与HPV疫苗犹豫/反抗的可能性显著相关。本研究显示了在科威特女性大学生中，支持疫苗阴谋论信念对人乳头瘤病毒疫苗接种意愿的不利影响。在旨在减轻HPV癌症负担的疫苗促销工作中应该考虑到这一点。

A substantial burden of high-risk human papillomavirus (HPV) infections and HPV-related cancers can be mitigated by vaccination. The current study aimed to investigate the willingness of female students at the University of Kuwait to get HPV vaccination and its possible association with general vaccine conspiracy beliefs (VCBs). This cross-sectional survey study was conducted during September-November 2022 using a validated VCB scale as the survey instrument. The final sample comprised 611 respondents with a median age of 22 y and a majority of Arab ethnicity (n = 600, 98.2%). Only 360 respondents (56.9%) heard of HPV before participation and these students showed an above-average level of HPV knowledge (mean knowledge score of 12.7 ± 2.6 out of 16 as the maximum score), of whom only 33 self-reported HPV vaccine uptake (9.2%). The willingness to accept free-of-charge HPV vaccination was seen among 69.8% of the participants, with 20.1% who were hesitant and 10.1% who were resistant. The acceptance of HPV vaccination if payment is required was 23.1%. Reasons for HPV vaccine hesitancy/resistance included complacency to the HPV disease risks, lack of confidence in HPV vaccination, and inconvenience. The embrace of VCBs was associated with significantly higher odds of HPV vaccine hesitancy/resistance. The current study showed the detrimental impact of endorsing vaccine conspiracy beliefs manifested in lower intention to get HPV vaccination among female university students in Kuwait. This should be considered in vaccine promotion efforts aiming to reduce the burden of HPV cancers.