睾丸肿瘤是男性最常见的恶性肿瘤之一。疾病的一种侵袭性少见亚型——睾丸绒毛膜癌，由于早期血行转移向多个器官和出现先进的症状而有更坏的预后。绒毛膜癌的特征包括精索肿块的年轻男性高举着人绒毛膜促性腺激素(β-hCG)。然而，当主要睾丸肿瘤过度利用其血液供应并自发性消退时，它被认为已经“燃尽”，留下转移的腹膜后淋巴结肿大、瘢痕组织和钙化。晚期睾丸癌的治疗可能被一种罕见的实体并发症所复杂，称为绒毛膜癌综合症，它以转移性肿瘤部位的快速致命性出血区分。既往有描述的绒毛膜癌综合症病例涉及肺部和胃肠道出血。我们介绍了一种罕见案例：一个34岁男性“燃尽”的转移性混合睾丸癌患者，患有绒毛膜癌综合症(CS)，接受了化疗，但出现了致命性大脑转移性出血。此外，在ChatGPT的协助下，我们报告了这一OpenAI工具在医学文献撰写中的潜在应用。版权所有©2023，Le等。

Testicular tumors are one of the most commonly observed malignancies among men. An aggressive and rare subtype of the disease, testicular choriocarcinoma, has a worse prognosis due to the tendency of early hematogenous spread to multiple organs and advanced symptoms at presentation time. Characteristic features of choriocarcinoma include elevated beta human chorionic gonadotropin (β-hCG) in a young male with testicular mass. However, when the primary testicular tumor overutilizes its blood supply and spontaneously regresses, it is presumed to have been "burnt out" with remnants evident by metastatic retroperitoneal lymphadenopathy, scarred tissue, and calcifications. Treatment of advanced testicular cancer may be complicated by a rare entity known as choriocarcinoma syndrome, distinguished by rapid and fatal hemorrhaging of metastatic tumor sites. Prior described cases of choriocarcinoma syndrome involve pulmonary and gastrointestinal hemorrhages. We present an uncommon case of a 34-year-old male with a "burnt out" metastatic mixed testicular cancer who presented with choriocarcinoma syndrome (CS) treated with chemotherapy but developed deadly hemorrhaging of brain metastases. In addition, with the assistance of ChatGPT, we report our experience with this OpenAI tool and its potential uses in medical literature writing.Copyright © 2023, Le et al.