研究动态
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布鲁加达样心电图模式与涉及右心室流出道的肿瘤 - 病例系列和文献综述。

BRUGADA-LIKE ECG PATTERN AND TUMORS INVOLVING RIGHT VENTRICULAR OUTFLOW TRACT - CASE SERIES AND LITERATURE REVIEW.

发表日期:2023
作者: Waldemar Elikowski, Natalia Fertała, Magdalena Zawodna-Marszałek, Agnieszka Kwiecien-Zaparty, Stanisław Łazowski, Paweł Skrzywanek, Marcin Zytkiewicz
来源: HEART & LUNG

摘要:

机械心脏压缩,包括纵隔肿瘤的压迫,可能导致布氏型心电图(ECG)图案。此类ECG图案也可能在阻塞右心室流出道(RVOT)的心脏内肿瘤中观察到。到目前为止已经报道了8例涉及RVOT的肿瘤和布氏型ECG的情况,其中4例生长在纵隔区(包括一例炎性肿块),3例位于心脏内,1例是组织化的心包血肿。作者介绍了另外3例RVOT心脏内转移性肿瘤和布氏型ECG图案的病例;右前导联凸起的ST段升高。所有患者均无心血管疾病或明显的恶性心律失常家族史。ECG检查是例行的,所有患者均没有胸痛或心肌肌钙蛋白的升高。所有患者的肿瘤疾病均处于晚期。其中一位76岁男性患者患有4种肿瘤:膀胱癌正在接受化疗,而前列腺癌、舌癌和肺癌多年前已经切除,未发现局部复发的迹象。另一位78岁女性患者,在静脉血栓栓塞发作后1个月被诊断出结肠癌。六个月之后,在病变切除后,在直肠中发现了腺癌的第二个病灶。第三位患者,一位65岁男性,在心脏转移诊断前一年进行了肾脏切除手术。
Mechanical heart compression, including that from mediastinal tumor, may cause Brugada-like ECG pattern. Such ECG pattern might also be observed in intracardiac tumor obstructing the right ventricular out"ow tract (RVOT). Eight cases with Brugada-like ECG and tumors involving RVOT have been described so far; 4 growing in the mediastinum (with one example of in"ammatory mass), 3 with intracardiac location, and 1 being an organized pericardial hematoma. The authors present other 3 cases of intracardiac metastatic tumors in RVOT and Brugada-like ECG pattern with coved ST-segment elevation in the right precordial leads. All patients had negative history of cardiovascular disease or familiar malignant arrhythmia occurrence. ECG were done routinely; none of the patients had chest pain or an increased level of cardiac troponins. In all patients, neoplastic disease was at advanced stage. A 76-year-old male, had a history of four neoplasms: bladder cancer was being treated with chemotherapy, while prostate, tongue, and lung cancers had been resected years ago and no signs of local relapse were found. A 78-year-old female, was diagnosed with colon cancer 1 month after an episode of venous thromboembolism. Six months after the resection of cancer, second focus of adenocarcinoma was found in the rectum. Third patient, a 65-year-old-male had undergone nephrectomy for renal cancer a year before cardiac metastasis diagnosis.