上皮卵巢癌手术的腹腔镜选择。简要回顾。
Laparoscopic selection for surgery in epithelial ovarian cancer. A short review.
发表日期:2023 Mar
作者:
V Ghirardi, A Fagotti, G Scambia
来源:
Best Pract Res Cl Ob
摘要:
腹腔镜在卵巢癌患者中作为治疗选择方法的角色在早期和晚期疾病中接受着外科实践方面越来越多的关注。当疾病仅限于卵巢时,需要在手术中使用腹腔镜评估肿瘤特征,以选择最佳手术方法,以避免癌细胞在手术中的泄漏,从而对患者预后产生负面影响。腹腔镜作为疾病分布评估工具,在晚期疾病的情况下,已被现行指南接受为有效的治疗策略选择。事实上,基于腹腔镜评估的腹腔内疾病扩散特征的已发表和验证的腹腔镜评分系统已被证明是优化细胞减灭的可靠预测因子。这随后减少了初步和间隔减灭手术设置中的探索性腹腔镜率。此外,在复发疾病的情况下,使用腹腔镜来预测是否可以实现完整的肿瘤切除,已由现有指南接受。在此情况下,结合腹腔镜和影像技术来管理敏感铂的复发性卵巢癌病例,在适当选择的患者中显示出高准确性,用于辅助再次减灭手术。在本文中,我们描述了腹腔镜在卵巢癌患者中治疗选择过程中的作用。
The role of laparoscopy as a treatment selection method in ovarian cancer patients is receiving growing attention in surgical practice in both early and advanced-stage disease. When the disease is confined to the ovary, intraoperative laparoscopic assessment of the tumour features is needed to select the best surgical approach in order to prevent intraoperative spillage of cancer cells which would negatively impact patient prognosis. The role of laparoscopy as a disease distribution assessment tool in cases of advanced-stage disease is now accepted by current guidelines as an effective treatment strategy selection. Indeed, a published and validated laparoscopic scoring system, based on laparoscopic assessed intra-abdominal disease dissemination features have been demonstrated to be a reliable predictor of optimal cytoreduction achievement. This subsequently reduces the exploratory laparotomy rate in both primary and interval debulking surgery setting. Furthermore, in cases of recurrent disease, the use of laparoscopy to predict whether complete tumour resection can be achieved is accepted by available guidelines. In this setting, the combination of laparoscopy and imaging techniques to manage platinum sensitive recurrent ovarian cancer cases showed a high accuracy in appropriately selected patients for secondary cytoreductive surgery. In this article we describe the role of laparoscopy in the treatment selection-process in ovarian cancer patients.