慢性呼吸系统疾病（CRDs）在全球范围内具有高流行率、患病率和死亡率。在COVID-19大流行之后，出院后再入院的患者增加了。对于某些人群，早期出院和居家护理可能会降低在家治疗的患者的医疗费用，而与住院患者相比。本研究旨在系统地审查居家护理对CRDs患者和COVID-19后综合症患者的有效性。我们将在MEDLINE、CENTRAL、Embase和PsycINFO上进行检索。我们将包括完整文本和摘要报告的随机对照试验（RCT）和非RCT研究，不限语言。我们将包括与CRDs或COVID-19后综合症诊断的成年人相关的研究，比较在院治疗与任何家庭医疗护理。我们将排除与神经、精神疾病、癌症或孕妇有关的研究参与者。两位审稿人将筛选摘要并选择符合条件的研究。为了调查偏倚风险，我们将使用Cochrane “风险偏倚”工具进行RCT，以及针对非RCT的干预措施偏差风险。我们将使用五个建议、评估、发展和评估（GRADE）考虑因素来评估证据的质量。患者和公众将参与审查的准备、执行和实施阶段。不需要道德批准，因为只分析已发表的数据。在同行评审的期刊和相关会议上发表结果将指导未来研究和医疗实践的方向。结果也将以简明的语言在社交媒体上传播，向对该主题感兴趣的社会和公众传播知识。©作者（或其雇主）2023。在CC BY-NC下允许重复使用。无商业重复使用。由BMJ出版。

Chronic respiratory diseases (CRDs) have a high prevalence, morbidity and mortality worldwide. After the COVID-19 pandemic, the number of patients readmitted after hospital discharge increased. For some populations, early hospital discharge and home healthcare may reduce health costs in patients treated at home when compared with those hospitalised. This study aims to systematically review the effectiveness of home healthcare for patients with CRDs and post-COVID-19 syndrome.We will search on MEDLINE, CENTRAL, Embase and PsycINFO. We will include randomised controlled trials (RCTs) and non-RCT studies reported in full text and abstracts. No language restriction will be applied. We will include studies related to adults with a diagnosis of CRDs or post-COVID-19 syndrome that compared in-patient hospital care with any home healthcare. We will exclude studies with participants with neurological, mental diseases, cancer or pregnant women. Two review authors will screen abstracts and select the eligible studies. To investigate the risk of bias, we will use the Cochrane 'Risk of Bias' tool for RCT, and the Risk of Bias In Non-randomised Studies-of Interventions for non-RCT. We will use the five Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) considerations to assess the quality of the evidence. Patients and the public will be involved in the preparation, execution and implementation phases of the review.No ethical approval is required because only published data will be analysed. The publication of the results in peer-reviewed journals and at relevant conferences will guide the direction of future research in the field and healthcare practice. The results will also be disseminated in plain language on social media to disseminate the knowledge to society and the public interested in the topic.© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.