研究动态
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The impact of additional pathology analysis on the diagnosis and management of soft tissue tumors: a 10-year retrospective study. 补充病理分析对软组织肿瘤的诊断和治疗的影响:一个10年回顾性研究。

The impact of additional pathology analysis on the diagnosis and management of soft tissue tumours: a 10-year retrospective study.

发表日期:2023 Mar 15
作者: Cameron Douglas, Alison Potter, Trent Davidson, Diane Schipp, Philip Crowe
来源: PATHOLOGY

摘要:

为了描述软组织肿瘤,病理学家经常使用专业的附加测试或从亚专业病理学家寻求意见,因为这种肿瘤很罕见或形态复杂。此外,亚专科肉瘤病理学家(例如位于澳大利亚悉尼的我们的三级转诊中心)可能会寻求进一步审查。本研究的目的是研究诊断和管理的外部审查对此的影响,从扫描在专门的肉瘤单元中诊断开始。我们汇总了10年期间所有外部附属测试和专家审查的结果,并将其表征为“确认”、“新的”或“没有明确的诊断”,然后记录这些进一步发现是否导致临床上具有意义的管理变化。136例中,103例患者的最初诊断得到了证实,29例患者得到了新的诊断,对于4例患者,诊断仍不确定。29名接受新诊断的患者中,有9名的处理方式发生了改变。本研究证明,我们专门的肉瘤单元的大多数诊断由我们的专家病理学家在额外的外部测试和审查中得到了确认,但外部审查确实为患者提供了额外的保障和好处。版权所有©2023澳大利亚病理学家学院。由Elsevier BV出版。保留所有权利。
In order to characterise soft tissue tumours, pathologists often utilise specialised additional tests, or may seek opinions from subspecialist pathologists due to rarity or complex morphology. Additionally, further review may be sought by subspecialist sarcoma pathologists, such as those at our tertiary referral centre in Sydney, Australia. The aim of this study was to examine the impact on diagnosis and management of this external review, following diagnosis at a specialised sarcoma unit. We collated the results of all additional external ancillary tests and specialist reviews over a 10-year period and characterised the impact on the preliminary diagnosis as 'confirmed', 'new' or 'no clear diagnosis'. We subsequently noted whether the additional findings resulted in a clinically significant change in management. Of the 136 cases sent away, 103 patients had their initial diagnosis confirmed, 29 patients received a new diagnosis and, for four patients, the diagnosis remained uncertain. Nine of the 29 patients receiving a new diagnosis had their management altered. This study demonstrated that within our specialised sarcoma unit, the majority of diagnoses provided by our specialist pathologists are confirmed on additional external testing and review, but external review does provide additional assurance and benefit to the patient.Copyright © 2023 Royal College of Pathologists of Australasia. Published by Elsevier B.V. All rights reserved.