癌前病变：从诊断到干预机会。
Pre-cancer: From diagnosis to intervention opportunities.
发表日期：2023 Apr 10
作者：
E Shelley Hwang, James Reading, Jun Yu, Gian Paolo Dotto, William M Grady, Bogdan Czerniak, Manuel Serrano
来源：
CANCER CELL
摘要：
癌变的多步过程暗示了既包括可能致癌细胞又包括其周围微环境中有前癌变改变状态的存在。专家讨论了一些已确定存在明确前癌变阶段的肿瘤类型，并提到了用于诊断和干预策略的关键生物学改变。Copyright © 2023. Published by Elsevier Inc.
The multi-step process of carcinogenesis implies the existence of pre-malignant yet altered states that involve both the potentially carcinogenic cell as well as its surrounding microenvironment. Experts discuss some tumor types for which clear pre-cancerous stages have been identified and mention key biological alterations used for diagnosis and intervention strategies.Copyright © 2023. Published by Elsevier Inc.