癌症相关疲劳的特征以及识别寻求疲劳相关管理的妇科癌症患者的有效模型。
Characteristics of Cancer-Related Fatigue and an Efficient Model to Identify Patients with Gynecological Cancer Seeking Fatigue-Related Management.
发表日期:2023 Apr 06
作者:
Ying-Wen Wang, Yu-Che Ou, Hao Lin, Kun-Siang Huang, Hung-Chun Fu, Chen-Hsuan Wu, Ying-Yi Chen, Szu-Wei Huang, Hung-Pin Tu, Ching-Chou Tsai
来源:
Cancers
摘要:
癌症相关疲劳(CRF)是妇科癌症患者中最常见的躯体不适。CRF经常被忽视,但它可以严重影响患者的生活质量。这项横断面研究旨在确定妇科癌症患者CRF的临床特征。问卷和第10版国际疾病分类(ICD-10)标准被用来确定CRF。入选患者根据接受的疲劳相关管理量被进一步分类。在入选的190名患者中,40.0%患有子宫内膜癌,28.9%患有宫颈癌,31.1%患有卵巢癌。根据ICD-10诊断标准,42.6%患有非癌相关疲劳,10%患有CRF,51%患有基于BFI-T问卷的疲劳。此外,77.9%的研究队列曾接受过疲劳相关管理。进一步分析表明,患有子宫内膜/宫颈癌、国际妇产科联合会分期>1、东部合作肿瘤组织表现评分≥1、癌症治疗反应不足以及在过去一周接受癌症治疗的患者接受更多疲劳相关管理的概率较高。从这些因素中发展出的五项预测模型可以帮助医生更有效地识别寻求更多疲劳相关管理的患者。这很重要,因为他们可能会遭受更深刻的CRF影响。
Cancer-related fatigue (CRF) is the most common somatic discomfort in patients with gynecological cancers. CRF is often overlooked; however, it can impair the patients' quality of life considerably. This cross-sectional study aimed to identify the clinical characteristics of CRF in gynecological cancer patients. Questionnaires and the International Classification of Diseases 10th Revision (ICD-10) criteria were used to identify CRF. The enrolled patients were further categorized according to the amount of fatigue-related management received. Of the enrolled 190 patients, 40.0% had endometrial cancer, 28.9% had cervical cancer, and 31.1% had ovarian cancer. On the basis of the ICD-10 diagnostic criteria, 42.6% had non-cancer-related fatigue, 10% had CRF, and 51% had BFI-T questionnaire-based fatigue. Moreover, 77.9% of the study cohort had ever received fatigue-related management. Further analysis showed that patients with endometrial/cervical cancer, International Federation of Gynecology and Obstetrics stage >1, Eastern Cooperative Oncology Group performance status score ≥1, inadequate cancer treatment response, and receiving cancer treatment in the past week had a higher probability of receiving more fatigue-related management. The five-item predictive model developed from these factors may help physicians recognize patients seeking more fatigue-related management more efficiently. This is important as they may suffer from a more profound CRF.