缺乏便宜和有效的生物标志物，用于影像引导下消融后预测肾细胞癌的预后。我们研究了2003年至2016年在本机构接受冷冻消融或射频消融治疗的本地小肾细胞癌（T1a或T1b）患者。共分析了203名患者。在多变量分析中，术前、术后和围手术期血液中NLR和PLR升高的患者与明显恶化的癌症特异性生存率、总体生存率和无转移生存率有关。此外，术前PLR的增加还与术后肾功能下降超过25%的患者的增加几率有关。综上所述，NLR和PLR是预测肿瘤和围手术期预后的有效预测因素；然而，应使用更大的外部数据集以在临床应用之前验证发现。

There is a lack of cheap and effective biomarkers for the prediction of renal cancer outcomes post-image-guided ablation. This is a retrospective study of patients with localised small renal cell cancer (T1a or T1b) undergoing cryoablation or radiofrequency ablation (RFA) at our institution from 2003 to 2016. A total of 203 patients were included in the analysis. In the multivariable analysis, patients with raised neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) pre-operatively, post-operatively and peri-operatively are associated with significantly worsened cancer-specific survival, overall survival and metastasis-free survival. Furthermore, an increased PLR pre-operatively is also associated with increased odds of a larger than 25% drop in renal function post-operatively. In conclusion, NLR and PLR are effective prognostic factors in predicting oncological outcomes and peri-operative outcomes; however, larger external datasets should be used to validate the findings prior to clinical application.