癌症研究中的下一个重大问题。
The next big questions in cancer research.
发表日期：2023 Apr 13
作者：
Sherene Loi, Jeffrey Settleman, Johanna A Joyce, C S Pramesh, Rene Bernards, Jia Fan, Juanita L Merchant, Javid Moslehi, William R Sellers
来源：
CELL
摘要：
我们对肿瘤发生和癌症进展以及不同类型的癌症临床治疗的理解在近年来发生了巨大的变化。然而，即使有了这些进展，科学家和肿瘤学家仍然面临着巨大的挑战，涉及分解参与的分子和细胞机制、治疗和生物标志物的开发，以及治疗后的生活质量等方面。在本文中，我们请研究人员就未来几年需要解决的重要问题发表评论。版权所有 © 2023 Elsevier Inc.。
Our understanding of tumorigenesis and cancer progression as well as clinical therapies for different cancer types have evolved dramatically in recent years. However, even with this progress, there are big challenges for scientists and oncologists to tackle, ranging from unpacking the molecular and cellular mechanisms involved to therapeutics and biomarker development to quality of life in the aftermath of therapy. In this article, we asked researchers to comment on the questions that they think are important to address in the coming years.Copyright © 2023 Elsevier Inc. All rights reserved.