启动免疫系统识别和消除癌细胞的治疗模式，被称为癌症免疫疗法，已经成为癌症治疗的一个独特支柱。其中最有前途的治疗方法包括治疗性疫苗、免疫检查点阻滞、双特异性T细胞结合剂（BiTEs）和养成细胞疗法。这些方法有一个共同的作用机制，即通过对肿瘤抗原诱导T细胞为基础的免疫响应，无论是内源性还是工程化的免疫响应。但是，免疫疗法的功效也取决于先天免疫系统，特别是抗原呈递细胞和免疫效应器之间的相互作用，这些细胞的参与同样正在研究之中。若想查看该快照，请打开或下载PDF。版权所有© 2023 Elsevier Inc.，保留所有权利。

Therapeutic modalities that engage the immune system to recognize and eliminate cancer, known as cancer immunotherapy, has emerged as a distinct pillar of cancer therapy. Among the most promising treatment approaches are therapeutic vaccines, immune checkpoint blockade, bispecific T-cell engagers (BiTEs) and adoptive cell therapies. These approaches share a common mechanism of action, which is elicitation of a T-cell-based immune response, either endogenous or engineered, against tumor antigens, but interactions between the innate immune system, particularly antigen-presenting cells, and immune effectors also underlie the efficacy of cancer immunotherapies and approaches engaging these cells are also under development. To view this SnapShot, open or download the PDF.Copyright © 2023 Elsevier Inc. All rights reserved.