卵巢原发性类癌是极为罕见的卵巢肿瘤，关于其临床特征和生存结果的数据十分有限。我们对56名患者进行了历史队列研究，以调查其临床特征。还评估了这些患者的总生存率、疾病特异性生存率、无复发生存率和潜在预后因素。这些患者的中位年龄为42.0岁（范围：20-71），平均肿瘤质量和类癌大小分别为7.3和0.4厘米。15名患者观察到升高的肿瘤标记物水平和10名患者观察到腹水。98.2%的患者的肿瘤局限于卵巢，只有一例患者有转移性疾病。手术是主要的治疗方法：37.5%的患者接受单侧输卵管卵巢切除术，25.0%的患者接受子宫切除术伴双侧输卵管卵巢切除术，21.4%的患者接受卵巢嚢肿切除术，10.7%的患者接受全面分期手术，5.4%的患者接受双侧输卵管卵巢切除术。有八名患者做了阑尾切除术，五名患者做了淋巴结清扫术，但没有显示肿瘤侵犯。化疗是唯一使用的辅助治疗，对四名患者进行了给药。病理分析显示，乳像类癌是最主要的亚型，发生在66.1%的患者中。 Ki-67指数在39名患者中报告，其中30名指数不超过3%，最高只达到5%。 初次治疗后只有一次复发，该患者在手术和奥曲肽治疗后经历了两次复发，保持稳定疾病。在中位随访时间为3.6年后，96.4%的患者没有疾病迹象，而3.6%的患者虽活着但仍患病。5年无复发生存率为97.9%，没有死亡发生。没有发现影响无复发生存率、总生存率或疾病特异性生存率的风险因素。卵巢原发性类癌患者的Ki-67指数极低，预后良好。选择保守手术，特别是单侧输卵管卵巢切除术。对于有转移性疾病的患者，可以考虑个体化辅助治疗。© 2023年作者。由北欧妇产科学会（NFOG）代表黑德琳出版社出版的《北欧妇产科学》（Acta Obstetricia et Gynecologica Scandinavica）上发表。

Primary ovarian carcinoids are extremely rare ovarian tumors, and there is limited data available on their clinical characteristics and survival outcomes.We conducted a historical cohort study of 56 patients to investigate their clinical characteristics. The overall survival, disease-specific survival, recurrence-free survival, and potential prognostic factors of these patients were also evaluated.The median age of these patients was 42.0 years (range: 20-71). The average mass and carcinoid size was 7.3 and 0.4 cm, respectively. Elevated tumor marker levels and ascites were observed in 15 and 10 patients, respectively. In 98.2% of the patients, tumors were confined to the ovary, while only one had metastatic disease. Surgery was the mainstay therapy: 37.5% of the patients underwent unilateral salpingo-oophorectomy, 25.0% underwent hysterectomy with bilateral salpingo-oophorectomy, 21.4% underwent ovarian cystectomy, 10.7% underwent comprehensive staging surgery, and 5.4% underwent bilateral salpingo-oophorectomy. Appendectomy and lymphadenectomy were performed in eight and five patients, respectively, but none showed tumor involvement. Chemotherapy was the only adjuvant treatment utilized, and was administered in four patients. Pathological analysis showed that strumal carcinoid was the most predominant subtype, occurring in 66.1% of the patients. The Ki-67 index was reported in 39 patients, 30 of which had an index of no more than 3%, with a maximum of only 5%. Only one relapse occurred after the initial treatment, and that patient experienced recurrences on two occasions, maintaining stable disease after surgery and octreotide therapy. After a median follow-up of 3.6 years, 96.4% of the patients achieved no evidence of disease, while 3.6% were alive with the disease. The 5-year recurrence-free survival rate was 97.9% and no death occurred. No risk factors for recurrence-free survival, overall survival, or disease-specific survival were identified.The Ki-67 indices were extremely low and prognoses were excellent in patients with primary ovarian carcinoids. Conservative surgery, especially unilateral salpingo-oophorectomy, is preferred. Individualized adjuvant therapy may be considered for patients with metastatic diseases.© 2023 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).