胰腺绒毛膜癌是一种罕见疾病，先前未报告同时伴发肝转移的情况。我们报告了一名46岁女性病例，其人绒毛膜促性腺激素β水平显著升高，18F-FDG PET/CT显示胰头、肝脏和淋巴结中存在FDG亲和性病变。初步诊断为胰腺绒毛膜癌伴转移，并通过 PET/CT 引导下的活检进行了进一步确认。随后植入125 I 粒子治疗胰腺绒毛膜癌病灶，有效缩小了肿瘤大小。5个月后出现了新的肝转移灶，该病例总体生存期为10个月。版权所有 © 2023 Wolters Kluwer Health，Inc.保留所有权利。

Pancreatic choriocarcinoma is a rare disease, and concurrent hepatic metastases have not previously been reported. We report a case of a 46-year-old woman with significantly elevated human chorionic gonadotropin β levels, and 18F-FDG PET/CT demonstrated FDG-avid lesions in the pancreatic head, liver, and lymph nodes. The initial diagnosis of pancreatic choriocarcinoma with metastases was made and further confirmed by PET/CT-guided biopsy. 125I seeds were then implanted to treat the pancreatic choriocarcinoma lesions, which effectively reduced the tumor size. New hepatic metastases have been observed after 5 months, and this case had an overall survival of 10 months.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.