研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

MSH-5: 恶性膝部肿瘤及时检测指标。

MSH-5: malignant knee tumors timely detection index.

发表日期:2023
作者: Gustavo Rivera-Saldívar, Rubén Torres-González, Alejandra Cario-Méndez, Romeo Técualt-Gómez, Rubén A Amaya-Zepeda, Armando Alcántara-Corona, Silvestre Fuentes-Figueroa
来源: Bone & Joint Journal

摘要:

骨肿瘤通常会被误诊导致治疗延误。骨肿瘤常常被误诊为肌腱炎,其中31%的病例对应于骨肉瘤,21%对应于尤文氏肉瘤。为了防止诊断延误,需要创建一个高度诊断怀疑度的临床放射学工具,以检测膝骨肿瘤。在墨西哥城的医疗高特别医院Dr. Victorio de la Fuente Narváez骨肿瘤服务中进行了一项临床测量学研究(敏感性、一致性和有效性)。收集了153名患者的特征。敏感性阶段包括3个领域(体征、症状和放射学)和12个项目。一致性评估使用ICC(0.944)、95%CI(0.865-0.977)、p <0.001和a-Cronbach(0.863)进行。指数获得了0.8的敏感度和0.882的特异度。该测试的阳性预测值为66.6%,阴性预测值为93.75%。阳性似然比为6.8,阴性似然比为0.2。使用r-Pearson(0.894;p <0.001)评估了有效性。设计了一个高度疑似的临床放射学指数,可以检测出恶性膝骨肿瘤,具有适当的敏感性、特异性、外观、内容、准则和构建有效性。版权所有:©2023 Permanyer。
Bone neoplasms are usually misdiagnosed causing a delay in their treatment. Bone neoplasms are usually confused with tendinitis, 31% of the cases corresponds to osteosarcomas and in 21% to Ewing's sarcomas.To create a clinical-radiographic instrument of high diagnostic suspicion of knee bone neoplasms to prevent a delay in diagnosis.A clinimetric study (sensitivity, consistency and validity) was performed in the bone tumor service, Hospital de Ortopedia de la Unidad Médica de Alta Especialidad Dr. Victorio de la Fuente Narváez, Instituto Mexicano del Seguro Social, in México City.Characteristics of 153 patients were collected. For the sensitivity phase, 3 domains (signs, symptoms, and radiology) and 12 items were included. Consistency was evaluated with ICC (0.944), 95%CI (0.865-0.977), p < 0.001 and a-Cronbach (0.863). Index obtained a sensitivity of 0.80 and a specificity of 0.882 were obtained. The positive predictive value of the test was 66.6% and the negative predictive value was 93.75%. The positive likelihood ratio was 6.8 and the negative likelihood ratio was 0.2. Validity was evaluated using r-Pearson (0.894; p < 0.001).A high suspicion clinical-radiographic index was designed to detect malignant knee tumors with adequate sensitivity, specificity, appearance, content, criteria, and construct validity.Copyright: © 2023 Permanyer.