Angelica的物种因其药用性而传统上被使用。最近的研究表明它们作为抗癌药物的潜在用途，使其成为进一步研究的领域。本综述旨在总结目前对Angelica物种潜在抗癌作用的了解，并为进一步研究提供见解。我们在Google Scholar、PubMed、ScienceDirect、Wiley、Science Citation Index Finder和Springer link上搜索与“Angelica”相关的信息，通过搜索“Angelica”、“Angelica phytochemical”、“Angelica antitumor effect”、“Angelica molecular mechanisms”和“Angelica clinical application”等关键词。包含的文章集中在Angelica植物的抗癌性质和临床研究上，而非与癌症相关的生物或植物化学研究则被排除在外。我们对于2001年至2023年出版的书籍、期刊和数据库进行了全面的搜索，共鉴定了186篇文章，用于本综述的分析其潜在的抗癌化学物质和治疗用途。Angelica属的活性化合物，如香豆素、呋喃香豆素、邻酚酸和多糖，通过各种机制表现出抗癌性能。具体物种，如A. archangelica、Angelica sinensis、A. gigas和A. ksiekie，通过靶向细胞通路、产生活性氧自由基以及诱导细胞凋亡的方案，具有作为抗癌药物的潜力。需要进一步研究Angelica属的性质，以开发新的癌症治疗方法。与合成的抗肿瘤药物相比，Angelica物种的植物化学物质具有潜在的抗癌作用，并需要进一步研究以开发有效、低成本和低毒性的癌症治疗方法。©2023 John Wiley & Sons Ltd。

Angelica species have been traditionally used for their medicinal properties. Recent studies have suggested their potential use as anticancer agents, making them an area of interest for further research. The review aims to summarize the current understanding of the potential anticancer effects of Angelica species and to provide insights for further research in this area. We searched for "Angelica" related information on Google Scholar, PubMed, ScienceDirect, Wiley, Science Citation Index Finder, and Springer link by searching keywords such as "Angelica," "Angelica phytochemical," "Angelica antitumor effect," "Angelica molecular mechanisms," and "Angelica clinical application." Included articles focused on the Angelica plant's anticancer properties and clinical studies, while non-cancer-related biological or phytochemical investigations were excluded. We conducted a comprehensive search of books, journals, and databases published between 2001 and 2023, identifying 186 articles for this narrative review. The articles were analyzed for their potential anticancer properties and therapeutic applications. Active compounds in the Angelica genus, such as coumarins, furanocoumarins, phthalides, and polysaccharides, exhibit anticancer properties through various mechanisms. Specific species, like A. archangelica, Angelica sinensis, A. gigas, and A. ksiekie, have the potential as anticancer agents by targeting cellular pathways, generating reactive oxygen species, and inducing apoptotic cell death. Further research into the properties of the Angelica genus is needed for developing new treatments for cancer. Phytochemicals from Angelica species possess potential as anticancer agents, requiring further research for the development of effective, low-cost, and low-toxicity cancer treatments compared to synthetic antitumor drugs.© 2023 John Wiley & Sons Ltd.