放射剂量学可以作为个体化分子放射治疗 (MRT) 手段的有用工具，以实现疗法诊断概念的不断发展。然而，附加的资源要求往往被视为实施的障碍。本指南讨论了剂量学要求，并演示了如何将剂量学方案针对中心可用的设施进行个性化定制。旨在帮助希望启动剂量学服务但可能没有一些更为成熟的治疗和剂量学中心的经验或资源的中心。本指南还讨论了多学科的方法和不同的人员需求，并回顾了关键设备示例，这些协议展示了核医学中实施主要治疗，包括治疗良性甲状腺疾病的 [131I]-NaI，用于神经内分泌肿瘤的 [177Lu]-DOTATATE 和 131 I-mIBG，以及用于无法切除的肝癌的 [90Y]-微粒子。© 2023作者，独家授权Springer-Verlag GmbH Germany、Springer Nature的一部分。

Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry and demonstrates how a dosimetry regimen can be tailored to the available facilities of a centre. The aim is to help centres wishing to initiate a dosimetry service but may not have the experience or resources of some of the more established therapy and dosimetry centres. The multidisciplinary approach and different personnel requirements are discussed and key equipment reviewed example protocols demonstrating these factors are given in the supplementary material for the main therapies carried out in nuclear medicine, including [131I]-NaI for benign thyroid disorders, [177Lu]-DOTATATE and 131I-mIBG for neuroendocrine tumours and [90Y]-microspheres for unresectable hepatic carcinoma.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.