镁对于各种细胞和酶过程至关重要，但经常被忽视或低估。低镁血症是癌症患者经常遇到的问题，会导致严重症状和发病率。在这篇评论中，我们提供了对镁的生理和调节以及癌症患者低镁血症的症状和迹象的深入分析。我们还研究了导致癌症患者镁失衡的原因和机制，特别关注可能导致低镁血症的癌症特定疗法。最后，我们提供了关于低镁血症管理的更新，包括口服和静脉补充，以及药物在治疗无反应病例中的作用。本评论旨在提高癌症患者健康管理者意识，重视癌症患者镁水平监测，并作为指南。未来的临床研究应该专注于镁的监测，对癌症进展的影响以及预防急性肾损伤的潜力。版权所有©2023 Elsevier Inc.。

Magnesium is crucial for various cellular and enzymatic processes, yet it often is overlooked or underappreciated. Hypomagnesemia, a deficiency of magnesium in the blood, is a frequent problem in cancer patients and can lead to severe symptoms and morbidity. In this review, we provide an in-depth analysis of the physiology and regulation of magnesium, and signs and symptoms of hypomagnesemia in cancer patients. We also examine the causes and mechanisms of magnesium imbalances in cancer patients, specifically focusing on cancer-specific therapies that can lead to hypomagnesemia. Finally, we provide updates on the management of hypomagnesemia, including oral and parenteral supplementation, as well as the role of drugs in cases that are resistant to treatment. This review aims to raise awareness among health care providers caring for cancer patients about the significance of monitoring magnesium levels in cancer patients and function as a guide. Future clinical studies should focus on magnesium monitoring, its impact on cancer progression, and its potential for preventing acute kidney injury.Copyright © 2023 Elsevier Inc. All rights reserved.