为评估主观社会地位（SSS）与代谢综合征（MetS）严重程度之间的关联及其对乳腺癌女性种族健康不平等性的潜在贡献进行研究。在美国10家医院进行多中心横断面研究，涉及到主要诊断为侵袭性乳腺癌的女性（n=1206），收集时间为2013年3月至2020年2月。参与者自我认定为非西班牙裔白人或黑人，接受身体和实验室检查以及有关社会经济参数、医疗史和行为风险的调查问卷。使用10阶梯马卡瑟尔评分来测量SSS。使用经过验证的Z得分来测量MetS严重程度。采用广义线性混合模型进行分析。采用多重插补方法处理缺失数据。平均年龄为58岁。相当收入和教育程度的情况下，黑人女性SSS平均值较白人女性低：在大专毕业生中为6.6（6.1-7.0）与7.7（7.54-7.79），在高收入类别（>75,000美元）的女性群体中分别为6.8（6.4-7.2）与7.6（7.5-7.8）。在多变量分析中，在控制年龄、收入、教育、饮食和体育锻炼等因素后，增加的SSS与减少的MetS-Z得分呈负相关，即每增加2阶梯，MacArthur评分下降0.10（-0.16至-0.04）。黑人患者的乳腺癌自我评定SSS低于白人患者，而此结果表明SSS与MetS严重程度密切相关，这些结果识别出可能可改变的因素，对解决种族不平等具有重要意义。© 2023. 作者，Springer Science+Business Media, LLC的独家许可，属于Springer Nature。

To evaluate the association of subjective social status (SSS) with metabolic syndrome (MetS) severity and its potential contribution to racial health disparities in women with breast cancer.Multicenter cross-sectional study (10 US hospitals) in women (n = 1206) with primary diagnosis of invasive breast cancer received during Mar/2013-Feb/2020. Participants, self-identified as non-Hispanic White or Black, underwent physical and laboratory examinations and survey questions assessing socioeconomic parameters, medical history, and behavioral risks. SSS was measured with the 10-rung MacArthur scale. MetS severity was measured with a validated Z-Score. Generalized linear mixed modeling was used to analyze the associations. Missing data were handled using multiple imputation.Average age was 58 years. On average, the SSS of Black women, given equivalent level of income and education, was lower than the SSS of White women: 6.6 (6.1-7.0) vs 7.7 (7.54-7.79) among college graduates and 6.8 (6.4-7.2) vs 7.6 (7.5-7.8) among women in the high-income category (> $75,000). In multivariable analysis, after controlling for age, income, education, diet, and physical activity, increasing SSS was associated with a decrease in MetS-Z score, - 0.10 (- 0.16 to - 0.04) per every 2 rung increase in the MacArthur scale.Black women with breast cancer rank their SSS lower than White women with breast cancer do at each level of income and education. As SSS is strongly associated with MetS severity these results identify potentially modifiable factors that contribute to racial disparities.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.