妇科癌症患者的身心疗法的有效性:一项系统综述和荟萃分析。
The Effectiveness of Mind-Body Therapies for Women With Gynecological Cancer: A Systematic Review and Meta-analysis.
发表日期:2023 Apr 24
作者:
Jing Wen Ong, Qian-Er Oriana Ong, Tea Metsävainio, Anne Vaajoki, Jing Ling Tian, Hong-Gu He
来源:
MEDICINE & SCIENCE IN SPORTS & EXERCISE
摘要:
身心疗法已成为支持性治疗中备受癌症患者欢迎的一种选择。迄今为止,尚未对身心疗法对妇科癌症女性健康结果的影响进行系统评价。本系统评价和荟萃分析旨在综合评估身心疗法对妇科癌症女性生活质量、焦虑、抑郁、与癌症相关的疼痛和疲劳的有效性。我们在7个数据库、试验登记和文献数据库中搜索和筛选了随机对照试验,时间跨度从数据库的开始到2021年12月。从符合条件的研究中提取数据,并使用Cochrane偏倚风险工具对每个研究的质量进行评估。使用RevMan 5.4进行荟萃分析,进行敏感性和亚组分析。使用推荐评估、开发和评估(GRADE)方法对研究的证据质量进行评估。共有9项试验被纳入。发现身心疗法在抑郁(标准化平均差异为-0.56;95%置信区间为-1.01至-0.11;P = 0.01)、疼痛(标准化平均差异为-1.60;95%置信区间为-3.14至-0.07;P = 0.04)和疲劳(标准差异化平均差异为-1.17;95%置信区间为-2.16至-0.18;P = 0.02)方面具有统计学意义的作用,但对于生活质量和焦虑没有明显作用。由于研究之间存在高偏倚和高异质性,证据质量较低。身心疗法对于减轻妇科癌症女性的抑郁、疼痛和疲劳是有效的。但是,由于证据质量较低,需要更多未来的研究以改进方法学。身心疗法可以作为一种额外策略来帮助管理妇科癌症女性的抑郁情绪、疼痛和疲劳。版权所有 ©2023 Wolters Kluwer Health,Inc.
Mind-body therapies (MBTs) have gained popularity among patients with cancer as a supportive therapy. To date, no systematic reviews have assessed the effect of MBTs on the health outcomes in women with gynecological cancer.This systematic review and meta-analysis aimed to synthesize the effectiveness of MBTs on quality of life, anxiety, depression, cancer-related pain, and fatigue among women with gynecological cancer.We searched and screened randomized controlled trials in 7 databases, trial registries, and gray literature from the databases' inception to December 2021. Data were extracted from eligible studies, with each study's quality assessed using the Cochrane risk-of-bias tool. Meta-analyses were conducted using RevMan 5.4. Sensitivity and subgroup analyses were performed. The quality of evidence across the studies was assessed using the Grading of Recommendations Assessment, Development and Evaluation approach.Nine trials were included. Statistically significant effects of MBTs on depression (standardized mean difference, -0.56; 95% confidence interval, -1.01 to -0.11; P = .01), pain (standardized mean difference, -1.60; 95% confidence interval, -3.14 to -0.07; P = .04), and fatigue (standardized mean difference, -1.17; 95% confidence interval, -2.16 to -0.18; P = .02) were observed, but not on quality of life and anxiety. The quality of evidence was low due to the high risks of bias and high heterogeneity among the studies.Mind-body therapies were effective in reducing depression, pain, and fatigue of women with gynecological cancer. However, the low quality of the evidence implies the need for more future studies with better methodologies.Mind-body therapies may be used as an additional strategy to help manage depressive mood, pain, and fatigue among women with gynecological cancer.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.