以突然死亡为首发症状的血管内大B细胞淋巴瘤。
Intravascular Large B-cell Lymphoma Presenting as Sudden Death.
发表日期:2023 Apr 20
作者:
Nicole R Jackson
来源:
Cell Death & Disease
摘要:
血管内大B细胞淋巴瘤是成熟B淋巴瘤细胞限制于血管内空间的少见非何杰金淋巴瘤亚型。该疾病因缺乏明确的肿瘤块、可以影响身体的任何部分、伴随着不确定的症状和多样的临床发现而难以捉摸,导致延迟或漏诊,即使在验尸时也是如此。本文介绍一位女性患者,她在前往急诊科不久后因血管内大B细胞淋巴瘤而去世,通过尸解检查诊断,增加了对这种罕见疾病的认识,并引起验尸和法医病理学家的重视。版权所有 © 2023 Wolters Kluwer Health,Inc. 保留所有权利。
Intravascular large B-cell lymphoma is a rare subset of non-Hodgkin lymphoma composed of mature B lymphoma cells confined to the intravascular space. This disease remains elusive because it lacks a discrete tumor mass, can affect any part of the body, and has vague symptoms paired with heterogeneous clinical findings resulting in delayed or missed accurate diagnosis, even at postmortem examination. This is a case of a woman who died within hours of presenting to the emergency department with a diagnosis of intravascular large B-cell lymphoma made through autopsy examination, adding to the knowledge of this rare disease and bringing it to the attention of practicing autopsy and forensic pathologists.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.