临床实践指南帮助卫生专业人员（HPs）做出决策。尽管开发成本高昂，但许多指南在临床设置中没有得到实施。本文描述了一项评估环境因素的研究，以制定临床指南的实施策略，用于解决澳大利亚癌症医院普遍而烦恼的问题——与癌症相关的疲劳（CRF）。通过对消费者和多学科HPs进行面试和焦点小组讨论的定性调查，探讨了加拿大CRF指南的关键建议。四个HP焦点小组研究了具体建议的可行性，而一个消费者焦点小组则研究了管理CRF的经验和优先考虑。利用设计加速实施研究的快速内容分析的方式对音频记录进行了分析。实施策略由实施研究的统一实施框架指导。共有五名消费者和31名多学科HP参加了八个面试和五个焦点小组讨论。HP疲劳管理的主要障碍包括知识和时间的不足，缺乏易于获得的筛查和管理工具或转诊途径。消费者的障碍包括在短暂的卫生咨询期间优先考虑癌症控制，耐力不足以应对疲劳的延长或额外就诊，以及HP对疲劳的态度。最佳疲劳管理的促进因素包括与现有医疗保健实践的一致性、增加HP CRF指南和工具的知识以及改善转诊途径。消费者认为，在治疗过程中解决疲劳，包括自我监测的个人疲劳预防或管理计划，非常重要。消费者更喜欢在诊所外管理疲劳，并使用远程医疗咨询。应该试行减少障碍和利用促进因素使用指南的策略。方法应包括（1）忙碌HP易于获取的知识和实践资源，（2）对患者和他们的HP而言，时间效率高的过程以及（3）与现有实践的过程相一致。癌症护理的资金必须使最佳支持性护理成为可能。©2023. Crown.

Clinical practice guidelines assist health professionals' (HPs) decisions. Costly to develop, many guidelines are not implemented in clinical settings. This paper describes an evaluation of contextual factors to inform clinical guideline implementation strategies for the common and distressing problem of cancer-related fatigue (CRF) at an Australian cancer hospital.A qualitative inquiry involving interviews and focus groups with consumers and multidisciplinary HPs explored key Canadian CRF guideline recommendations. Four HP focus groups examined the feasibility of a specific recommendation, while a consumer focus group examined experiences and preferences for managing CRF. Audio recordings were analysed using a rapid method of content analysis designed to accelerate implementation research. Strategies for implementation were guided by the Consolidated Framework for Implementation Research.Five consumers and 31 multidisciplinary HPs participated in eight interviews and five focus groups. Key HP barriers to fatigue management were insufficient knowledge and time; and lack of accessible screening and management tools or referral pathways. Consumer barriers included priority for cancer control during short health consultations, limited stamina for extended or extra visits addressing fatigue, and HP attitudes towards fatigue. Enablers of optimal fatigue management were alignment with existing healthcare practices, increased HP knowledge of CRF guidelines and tools, and improved referral pathways. Consumers valued their HPs addressing fatigue as part of treatment, with a personal fatigue prevention or management plan including self-monitoring. Consumers preferred fatigue management outside clinic appointments and use of telehealth consultations.Strategies that reduce barriers and leverage enablers to guideline use should be trialled. Approaches should include (1) accessible knowledge and practice resources for busy HPs, (2) time efficient processes for patients and their HPs and (3) alignment of processes with existing practice. Funding for cancer care must enable best practice supportive care.© 2023. Crown.