子宫内膜癌（EC）的大多数女性预后良好且可治愈。然而，治疗相关的盆腔功能影响可能会影响长期生活质量。为了更好地了解这些问题，我们探讨了EC女性患者报告的结果与盆腔磁共振成像（MRI）特征之间的相关性。EC组织学诊断女性在术前签署知情同意书，并在术前、6周和6个月的随访中完成经过验证的女性性功能指数（FSFI）和盆底功能障碍指数（PFDI）问卷调查。在6周和6个月时进行具有动态盆底序列的盆腔MRI检查。共有33名女性参加了这项前瞻性试验。只有53.7％的女性受过医生有关性功能的询问，而92.4％的女性认为自己应该被问及。随着时间的推移，性功能变得更加重要。基线FSFI较低，在6周时下降，在6个月时上升超过基线。T2加权图像上的高信号阴道壁（10.9 vs. 4.8，p = .002）和完整的Kegel功能（9.8 vs. 4.8，p = .03）与较高的FSFI有关。随着时间的推移，PFDI评分趋向于改善盆底功能。MRI上的盆腔粘连与更好的盆底功能有关（23.0 vs. 54.9，p = .003）。尿道过度活动（48.4 vs. 21.7，p = .01）、膀胱脱垂（65.6 vs. 24.8，p < .0001）和直肠脱垂（58.8 vs. 18.8，p < .0001）预示着较差的盆底功能。使用盆腔MRI来量化解剖和组织变化可能有助于盆底和性功能的风险分层和反应评估。患者明确表达了需要在EC治疗过程中关注这些结果。版权所有 © 2023 Elsevier Inc.发表。

Most women with endometrial cancer (EC) have an excellent prognosis and may be cured. However, treatment-related pelvic functional impacts may affect long-term quality of life. To better understand these concerns, we explored correlations between patient-reported outcomes and pelvic magnetic resonance imaging (MRI) features in women treated for EC.Women with histologic diagnosis of EC were consented preoperatively and completed the validated Female Sexual Function Index (FSFI) and Pelvic Floor Dysfunction Index (PFDI) questionnaires at preoperative, 6-week, and 6-month follow-up visits. Pelvic MRIs with dynamic pelvic floor sequences were performed at 6 weeks and 6 months.A total of 33 women participated in this prospective pilot study. Only 53.7% had been asked about sexual function by providers while 92.4% thought they should have been. Sexual function became more important to women over time. Baseline FSFI was low, declined at 6 weeks, and climbed above baseline at 6 months. Hyperintense vaginal wall signal on T2-weighted images (10.9 vs. 4.8, p = .002) and intact Kegel function (9.8 vs. 4.8, p = .03) were associated with higher FSFI. PFDI scores trended toward improved pelvic floor function over time. Pelvic adhesions on MRI were associated with better pelvic floor function (23.0 vs. 54.9, p = .003). Urethral hypermobility (48.4 vs. 21.7, p = .01), cystocele (65.6 vs. 24.8, p < .0001), and rectocele (58.8 vs. 18.8, p < .0001) predicted worse pelvic floor function.Use of pelvic MRI to quantify anatomic and tissue changes may facilitate risk stratification and response assessment for pelvic floor and sexual dysfunction. Patients articulated the need for attention to these outcomes during EC treatment.Copyright © 2023. Published by Elsevier Inc.