针对传统药物的不足，目前在新型纳米医学的研究中使用了各种纳米颗粒。因此，本文对基于纳米颗粒的药物在呼吸系统疾病治疗中的效果进行了全面和最新的综述，包括基础和临床研究。我们在PubMed、Web of Knowledge和Scopus等数据库中搜索了截至2022年8月底与纳米颗粒对呼吸系统疾病的影响相关的文献。作为一种新的工具，纳米医学为肺疾病的治疗提供了有前途的应用。纳米材料的基本组成和内在特性显示了它们在治疗肺疾病方面的有效性。不同纳米药物的效率在哮喘、慢性阻塞性肺病（COPD）、肺纤维化（PF）、肺癌、肺部感染和其他肺部疾病的实验动物模型中已得到证实，这证实了它们在改善呼吸系统疾病方面的作用。各种类型的纳米材料，如碳纳米管、树枝状聚合物、聚合物纳米颗粒、脂质体、量子点以及金属和金属氧化物纳米颗粒，在呼吸系统疾病治疗中展示了治疗效果，这可能为各种呼吸系统疾病的新疗法提供了可能，有望增加药物的疗效并减少副作用。 版权所有 © 2023 Taghavizadeh Yazdi, Qayoomian, Beigoli and Boskabady.

Various nanoparticles are used in the discovery of new nanomedicine to overcome the shortages of conventional drugs. Therefore, this article presents a comprehensive and up-to-date review of the effects of nanoparticle-based drugs in the treatment of respiratory disorders, including both basic and clinical studies. Databases, including PubMed, Web of Knowledge, and Scopus, were searched until the end of August 2022 regarding the effect of nanoparticles on respiratory diseases. As a new tool, nanomedicine offered promising applications for the treatment of pulmonary diseases. The basic composition and intrinsic characteristics of nanomaterials showed their effectiveness in treating pulmonary diseases. The efficiency of different nanomedicines has been demonstrated in experimental animal models of asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis (PF), lung cancer, lung infection, and other lung disorders, confirming their function in the improvement of respiratory disorders. Various types of nanomaterials, such as carbon nanotubes, dendrimers, polymeric nanomaterials, liposomes, quantum dots, and metal and metal oxide nanoparticles, have demonstrated therapeutic effects on respiratory disorders, which may lead to new possible remedies for various respiratory illnesses that could increase drug efficacy and decrease side effects.Copyright © 2023 Taghavizadeh Yazdi, Qayoomian, Beigoli and Boskabady.