血小板膜模仿纳米粒子（PMINs）是一种新颖的药物传递系统，模仿了血小板膜的结构和功能。 PMINs模仿血小板的表面标记物来靶向特定细胞并传输治疗药物。 PMINs通过将药物并入血小板膜并封装在纳米颗粒支架中来进行工程化。这使得PMINs能够在血液中循环并与靶细胞高度特异性结合，减少非靶效应并提高治疗效果。 PMINs的工程化包括几个阶段，包括分离和纯化血小板膜，将治疗药物整合到膜中，以及将膜封装在纳米颗粒支架中。除了参与癌症、动脉粥样硬化和类风湿性关节炎等一些病理条件外，血小板对人体的生理过程至关重要。本研究包括血小板膜类似纳米粒子的制备和表征，并重点关注它们在靶向治疗癌症、免疫性疾病、动脉粥样硬化、光疗等方面的最新进展。 PMINs是一种将血小板膜与纳米粒子的优点相结合的潜在药物传递系统。创造具有特定治疗药物和表面标记物的PMINs的能力为靶向药物管理提供了新的可能性，并有可能彻底改变医学的实践方式。尽管需要更多的研究来优化工程过程并评估PMINs在临床试验中的有效性和安全性，但这项技术具有很大的潜力。版权所有© Bentham科学出版社；有关任何查询，请发送电子邮件至epub@benthamscience.net。

Platelet membrane imitating nanoparticles (PMINs) is a novel drug delivery system that imitates the structure and functionality of platelet membranes. PMINs imitate surface markers of platelets to target specific cells and transport therapeutic cargo. PMINs are engineered by incorporating the drug into the platelet membrane and encapsulating it in a nanoparticle scaffold. This allows PMINs to circulate in the bloodstream and bind to target cells with high specificity, reducing off-target effects and improving therapeutic efficacy. The engineering of PMINs entails several stages, including the separation and purification of platelet membranes, the integration of therapeutic cargo into the membrane, and the encapsulation of the membrane in a nanoparticle scaffold. In addition to being involved in a few pathological conditions including cancer, atherosclerosis, and rheumatoid arthritis, platelets are crucial to the body's physiological processes. This study includes the preparation and characterization of platelet membrane-like nanoparticles and focuses on their most recent advancements in targeted therapy for conditions, including cancer, immunological disorders, atherosclerosis, phototherapy, etc. PMINs are a potential drug delivery system that combines the advantages of platelet membranes with nanoparticles. The capacity to create PMMNs with particular therapeutic cargo and surface markers provides new possibilities for targeted medication administration and might completely change the way that medicine is practiced. Despite the need for more studies to optimize the engineering process and evaluate the effectiveness and safety of PMINs in clinical trials, this technology has a lot of potential.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.