在意大利佩鲁贾大学兽医教学医院和安尼库拉提鲁斯兽医诊所（意大利特尔尼）的狗群中进行了一项回顾性研究，以调查卵巢肿瘤的发生率、临床表现和超声学结果。研究期从2005年1月至2021年12月。共有1910只狗患有肿瘤，但只有其中的35只（1.8%），来自不同品种和年龄，发现患有卵巢肿瘤。基于临床表现进行了卵巢超声检查；通过超声结果提示卵巢子宫切除术和卵巢病理评估实现了诊断。在我们的研究中，患有卵巢肿瘤的母犬的年龄范围为3至20岁（平均9.6 ± 3.8）。卵巢肿块的组织病理学结果显示：16例颗粒细胞瘤（46%），7例腺瘤（20%），5例腺癌（14%），2例畸胎瘤（6%），1例平滑肌瘤（3%），1例黄体瘤（3%），1例囊肿瘤（3%），1例畸胎癌（3%），1例血管肉瘤（3%）。特别是在临床症状方面，69%的母犬表现出发情周期异常（间隔较短、持续发情、间隔延长）。其他主要临床症状包括腹部膨胀、可触及的腹部肿块、外阴阴道流出物、多尿/多饮水、乳腺肿块。当有时，实验室检查发现轻度贫血和白细胞增多伴中性粒细胞增多。肿瘤在超声学上主要被分为以下三类：主要为实性的12/35（34%）（1例腺瘤，4例腺癌，1例畸胎癌，1例血管肉瘤，1例平滑肌瘤，1例黄体瘤，1例颗粒细胞瘤，1例囊肿瘤，1例畸胎瘤）；实性与囊性成分都存在的13/35（37%）（9例颗粒细胞瘤，2例腺瘤，1例腺癌，1例畸胎瘤）；主要为囊性的10/35（29%）（6例颗粒细胞瘤，4例腺瘤）。在我们的研究中，超声检查使我们能够怀疑无症状的患者患有卵巢肿瘤，这些患者因繁殖管理或预防性健康检查而前来就诊。根据我们的数据，我们建议每年6岁起进行一次完整的生殖系统检查。然而，在繁殖管理过程中发现年轻个体患有卵巢肿瘤，提示应将生殖道的例行超声检查纳入常规。版权所有 © 2023. 由 Elsevier Inc. 出版。

A retrospective study was carried out to investigate incidence, clinical signs and ultrasonographic findings of ovarian tumours in a population of dogs referred to the Veterinary Teaching Hospital of the University of Perugia (Italy) and Anicura Tyrus Veterinary Clinic (Terni, Italy). The period of study ranged from January 2005 to December 2021. A total of 1910 dogs were affected by neoplasia but only 35 of them (1.8%), of different breeds and ages, were found to have ovarian tumours. Ultrasound of the ovaries was performed based on clinical signs; the diagnosis was achieved after ultrasound findings prompted ovariohysterectomy and ovarian pathologic evaluation In our study, the age of bitches affected by ovarian neoplasia ranged from 3 to 20 years (mean 9.6 ± 3.8). The histopathological findings of ovarian masses identified 16 granulosa cell tumours (GCT) (46%), 7 adenomas (20%), 5 adenocarcinomas (14%), 2 teratomas (6%), 1 leiomyoma (3%), 1 luteoma (3%), 1 tecoma (3%), 1 dysgerminoma (3%), and 1 haemangiosarcoma (3%). In particular, with respect to clinical signs, 69% of bitches showed abnormalities of estrus cycle (short interestral interval, persistent estrus, prolonged interestral interval). The other main clinical signs included abdominal distention, palpable abdominal mass, vulvovaginal discharge, polyuria/polydipsia, mammary masses. When present, the laboratory abnormalities were slight anemia and leucocytosis with neutrophilia. The tumours were ultrasonographically classified as mainly solid: 12/35 (34%) (1 adenoma, 4 adenocarcinomas, 1 dysgerminoma, 1 haemangiosarcoma, 1 leyomioma, 1 luteoma, 1 GCT, 1 tecoma, 1 teratoma); solid with cystic component 13/35 (37%) (9 GCT, 2 Adenomas, 1 adenocarcinoma, 1 teratoma); and mainly cystic 10/35 (29%) (6 GCTs, 4 adenomas). In our study, the ultrasound examination allowed us to suspect ovarian neoplasia in asymptomatic subjects referred for breeding management or for preventive health check. On the basis of our data, we proposed to perform a complete periodic examination of the reproductive system once a year from 6 years. Nevertheless, the presence of ovarian neoplasms found in young subjects, during breeding management, suggest including routine ultrasound examination of the reproductive tract.Copyright © 2023. Published by Elsevier Inc.