脑转移作为全球公共卫生领域的一个日益严重的问题，尽管转移性疾病患者的存活率有所改善。转移灶本身以及治疗过程中的后遗症对患者生存、功能和生活质量的相互联系构成了重要决定因素，这要求在临床护理和研究中采取多维度的方法。在2022年9月虚拟国家癌症研究所研讨会上，关键利益相关者汇聚一堂，就研究重点进行讨论，旨在找出脑转移患者面临的需求缺口，以实现病患结果的重要进展。本政策回顾概述了现有知识差距、合作机会和关于脑转移研究的共识重点和未来方向的具体建议。要取得重大的研究进展，需要加强个人组织和联盟之间的协调合作。更重要的是，需要不断积极地吸引患者和患者倡导者的参与，以确保所有努力的方向都能反映在患者护理的背景下最有意义的事情。Copyright © 2023 Elsevier Ltd. All rights reserved.

Brain metastases are an increasing global public health concern, even as survival rates improve for patients with metastatic disease. Both metastases and the sequelae of their treatment are key determinants of the inter-related priorities of patient survival, function, and quality of life, mandating a multidimensional approach to clinical care and research. At a virtual National Cancer Institute Workshop in September, 2022, key stakeholders convened to define research priorities to address the crucial areas of unmet need for patients with brain metastases to achieve meaningful advances in patient outcomes. This Policy Review outlines existing knowledge gaps, collaborative opportunities, and specific recommendations regarding consensus priorities and future directions in brain metastases research. Achieving major advances in research will require enhanced coordination between the ongoing efforts of individual organisations and consortia. Importantly, the continual and active engagement of patients and patient advocates will be necessary to ensure that the directionality of all efforts reflects what is most meaningful in the context of patient care.Copyright © 2023 Elsevier Ltd. All rights reserved.