在一项实际世界试验中，我们先前证明了一种新型肿瘤医院居家护理计划（文献待审）与减少医疗利用和成本有关。在本研究中，我们试图了解根据性别、年龄、区域层面收入中值、Charlson共病指数和当前使用的全身抗癌治疗等具体患者亚组对该计划（文献待审）的影响。回顾性病例对照研究，比较 [机构名称待审] 中入住 [文献待审] 的病人、与接受常规护理的病人之间的电子数据仓库中的患者。总计169名入住 [文献待审] 的病人与198名接受常规护理的病人进行比较。对性别（女性 vs 男性）、年龄（≥65岁 vs <65岁）、收入（≥78,735美元 vs <78,735美元）、Charlson共病指数（≥2 vs <2）和当前使用全身抗癌治疗 vs 未使用全身抗癌治疗等五个二分亚组进行评估。将亚组与接受常规护理的患者进行比较。主要结果包括30天费用、住院天数、非计划住院和紧急就诊次数。入住 [文献待审] 与所有4个医疗成本和利用结果的降低有关。有利于入住 [文献待审] 的结果在每个研究的亚组中至少达到了统计学显著性（P < .05）的2个结果中。在某些结果类别中，没有从 [文献待审] 入住中获得统计学显著优势的亚组中，没有一个亚组支持常规护理。[文献待审] 的入住减少了非计划医疗利用和降低了各种患者亚组的成本，表明该服务的整体效益是一致的。肿瘤患者应考虑将医院居家模型作为提高护理质量和效率的方式。版权所有 © 2023。Elsevier Inc.出版。

In a real-world trial, we previously demonstrated that [blinded for review], a novel oncology hospital at home program, was associated with reduced health care utilization and costs. In this study, we sought to understand the impact of [blinded for review] in specific patient subgroups defined by sex, age, area-level median income, Charlson Comorbidity Index, and current use of systemic anticancer therapy.Retrospective case-control study of the [Institution blinded for review]. Electronic Data Warehouse of patients enrolled in [blinded for review] between August 2018 through October 2019 vs usual-care patients.A total of 169 patients admitted to [blinded for review] compared with 198 usual-care patients.Five dichotomous subgroups evaluated including sex (female vs male), age (≥65 vs <65), income (≥$78,735 vs <$78,735), Charlson Comorbidity Index (≥2 vs <2), and current systemic anticancer therapy use vs no current systemic anticancer therapy. Groups were compared with patients receiving usual care. Primary outcomes included 30-day costs, hospital length of stay, unplanned hospitalizations, and emergency room visits.Admission to [blinded for review] was associated with an overall reduction across all 4 health care cost and utilization outcomes. Outcomes favoring admission to [blinded for review] achieved statistical significance (P < .05) in at least 2 of the 4 outcomes for each subgroup studied. Of the subgroups that did not achieve statistically significant benefit from [blinded for review] admission in some outcome categories, none of these subgroups favored usual care.Admission to [blinded for review] decreased utilization of unplanned health care and reduced costs across a wide spectrum of patient subgroups, suggesting overall consistent benefit from the service. Hospital at home models should be considered as a means by which the quality and efficiency of care can be maximized for patients with cancer.Copyright © 2023. Published by Elsevier Inc.