来源于扩散性神经内分泌系统细胞的类癌瘤是罕见的、生长缓慢的神经内分泌肿瘤，病情进展相对温和。大多数类癌瘤位于胃肠道和支气管肺系统。原发性卵巢类癌瘤罕见，仅占所有类癌瘤的1%。我们描述了一例罕见的原发性卵巢类癌瘤病例，表现为慢性便秘，没有其他类癌瘤症状，如潮红、腹泻和喘息。 一名51岁绝经后的慢性便秘女性因常规检查其先前存在的子宫肌瘤而前往诊所就诊。她于3年前行了痔疮手术。体格检查显示腹部柔软，无直接或反弹性压痛。经阴道超声检查发现两个子宫肌瘤边缘下子宫肌瘤，并与先前的超声检查结果相比尺寸增大。右卵巢也检测到一个3cm的高回声肿块。她的血液和尿液检查无异常，盆腔无腹水。她的CA-125水平正常，为5.5单位/毫升。 患者因子宫肌瘤增大和右卵巢肿块接受了机器人辅助子宫切除术和右附件切除术。随后，根据病理和免疫组化结果，她被诊断为原发性卵巢类癌瘤。肿块由滤泡和梁状类型的肿瘤细胞组成。它对泛细胞角蛋白和突触物质呈阳性反应，Ki-67增殖指数小于1%。随访正电子发射计算机断层扫描未发现远处转移。术后六个月，患者病情良好，没有复发迹象。 没有畸胎瘤成分的原发性卵巢类癌瘤很少见。根据免疫组化染色结果进行准确诊断至关重要。疾病早期的诊断与有利的预后相关，但定期随访是必需的。 © 2023作者。由Wolters Kluwer Health, Inc.发布。

Carcinoid tumors, derived from the cells of the disseminated neuroendocrine system, are rare, slow-growing neuroendocrine neoplasms that display a relatively indolent disease course. The majority of carcinoids are found within the gastrointestinal tract and bronchopulmonary system. Primary ovarian carcinoids are rare and account for merely 1% of all carcinoid tumors. We describe our experience of a rare case of primary ovarian carcinoid, presenting as chronic constipation, with no other carcinoid symptoms such as flushing, diarrhea, and wheezing.A 51-year-old postmenopausal woman with chronic constipation visited the clinic for routine check-up of her preexisting uterine fibroids. She had undergone hemorrhoidectomy 3 years ago. Physical examination revealed a soft abdomen without direct or rebound tenderness. Transvaginal ultrasonography revealed two subserosal fibroids, which had increased in size compared with previous ultrasonographic findings. A 3 cm hyperechoic mass was also detected in the right ovary. Her blood and urine tests were unremarkable, with no ascites in the pelvic cavity. She had a normal CA-125 level of 5.5 units/mL.The patient underwent a robot-assisted hysterectomy and right salpingo-oophorectomy because of enlarging fibroids and the right ovarian mass. Subsequently, based on the pathological and immunohistochemical findings, she was diagnosed with a primary ovarian carcinoid. The mass consisted of the insular and trabecular types of tumor cells. It was positive for pan-cytokeratin and synaptophysin, and the Ki-67 proliferation index was less than 1%. A follow-up positron emission tomography-computed tomography revealed no distant metastasis. Six months postoperatively, the patient was doing well without any signs of recurrence.Primary ovarian carcinoids without teratoma components are rare. It is crucial to make an accurate diagnosis based on the immunohistochemical staining results. Diagnosis in the early stages of the disease are associated with a favorable prognosis, but regular follow-up is mandatory.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.