本研究的目标是讨论职业治疗对乳腺癌患者生活质量不同领域的影响。我们进行了文献检索，以查找截至2023年6月27日之前发表的文章，使用的数据库包括PubMed、Embase、Web of Science、Cochrane Library和Scopus。本研究报告遵循《系统评价和荟萃分析报告的首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analyses，简称PRISMA)的声明。确定了报告职业治疗对乳腺癌患者生活质量影响的随机对照试验。两位评阅者独立评估资格，提取数据，并确定偏倚风险。使用随机效应荟萃分析估计标准化均值差异(SMDs)及其95%置信区间(CIs)。使用Galbraith图、荟萃回归分析、亚组分析和敏感性分析来确定治疗效果的异质性。共包括8项研究，共计543名患者。实验组在整体健康(合并SMD=0.640，95% CI=0.251-1.028，P=.001)、身体健康(合并SMD=0.640，95% CI=0.251-1.028，P=.019)、社交健康(合并SMD=0.251，95% CI=0.011-0.490，P=.040)和认知功能(合并SMD=0.863，95% CI=0.266-1.460，P=.05)方面表现出更好的水平，并改善疲劳(合并SMD=-0.389，95% CI=-0.586到-0.192，P=.000)和角色功能(合并SMD=0.287，95% CI=0.029-0.546，P=.029)，相较于对照组。两组在情感健康(合并SMD=0.243，95% CI=-0.051到0.536，P=.105)和疼痛(合并SMD=-0.312，95% CI=-0.660到0.036，P=.079)方面表现出可比性。目前的证据显示，职业治疗可以改善乳腺癌患者的生活质量，尤其是整体健康、身体健康、社交健康、认知功能、疲劳和角色功能。版权所有©2023作者。由 Wolters Kluwer Health,Inc. 发表。

The objective was to discuss the impact of occupational therapy on different domains of quality of life in breast cancer patients. We performed a literature search to identify articles published before June 27, 2023, using the following databases: PubMed, Embase, Web of Science, Cochrane Library, and Scopus.The objective was to discuss the impact of occupational therapy on different domains of quality of life in breast cancer patients.We performed a literature search to identify articles published before June 27, 2023, using the following databases: PubMed, Embase, Web of Science, Cochrane Library, and Scopus.This study was reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Randomized controlled trials that reported the effects of occupational therapy on quality of life in breast cancer patients were identified. Two reviewers independently assessed eligibility, extracted data, and determined risks of bias. Pooled standardized mean differences (SMDs) with 95% confidence intervals (CIs) were estimated using random-effects meta-analyses. Galbraith plots, meta-regression analysis, subgroup analysis, and sensitivity analysis were used to identify heterogeneity in treatment effects.Eight studies were included, with a total of 543 patients. The experimental group exhibited better global health (pooled SMD = 0.640, 95% CI = 0.251-1.028, P = .001), physical health (pooled SMD = 0.640, 95% CI = 0.251-1.028, P = .019), social health (pooled SMD = 0.251, 95% CI = 0.011-0.490, P = .040), and cognitive function (pooled SMD = 0.863, 95% CI = 0.266-1.460, P = .05) and improve fatigue (pooled SMD = -0.389, 95% CI = -0.586 to -0.192, P = .000), and role function (pooled SMD = 0.287, 95% CI = 0.029-0.546, P = .029) than the control group. The 2 groups exhibited comparable emotional health (pooled SMD = 0.243, 95% CI = -0.051 to 0.536, P = .105) and pain (pooled SMD = -0.312, 95% CI = -0.660 to 0.036, P = .079).The current evidence shows that occupational therapy can improve the quality of life of breast cancer patients, especially their global health, physical health, social health, cognitive function, fatigue, and role function.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.