指数指骨近端骨样骨瘤的复发:一例新切除技术的病例报告。
Recurrent osteoid osteoma of the index proximal phalanx: A case report with a new resection technique.
发表日期:2023 Aug 04
作者:
Joseph Antoine Mouawad, Mohamad Omar Youssef Honeine, Joe Georges Ghanimeh, Perla Naji Audi, Khalil Tanios Khalil
来源:
Cellular & Molecular Immunology
摘要:
骨疣骨症是一种相对常见的良性骨形成病变,常发生在下肢和脊柱受侵的年轻成人。其特点是形成骨原质组织,也就是骨的前体组织,并会在受影响区域引起疼痛和活动受限。手部和手指的骨疣骨症罕见,因此构成了一个诊断上的挑战。本文得到了患者父亲的书面知情同意,允许刊登和分享与该患者有关的所有图像和临床数据。
我们报告了一例11岁女孩的病例,她的左手食指持续1年出现疼痛和肿胀,同时活动受限。非类固醇抗炎药可以缓解疼痛,但一旦停药疼痛会再次出现。一系列的检查显示食指近侧第二骨节颈部有溶骨坏死区,具有骨疣骨症的特征。我们进行了切除和骨移植手术,作为明确诊断骨疣骨症的治疗手段。然而,患者2年后再次出现以前的症状复发,其他检查表明骨疣骨症再次复发。为了解决复发问题,我们采用了改良的开放热肿瘤消融技术。热消融是一种微创手术,利用热量来破坏肿瘤细胞,已被证明对骨疣骨症的治疗有效。改良的开放方法通过一个小切口来进入肿瘤并通过之前经CT引导插入的Kirschner wire向受影响区域传递热量。
手术后1个月和1年,患者没有疼痛,没有放射学征象表明病变复发,显示病变已完全切除。总的来说,本例病例凸显了手部和手指的骨疣骨症的诊断和治疗的挑战。进一步研究需要加深我们对骨疣骨症潜在病因、潜在风险因素和最佳治疗方法的理解。
版权所有© 2023 作者(们)。由 Wolters Kluwer Health, Inc. 出版。
Osteoid osteoma is a relatively common benign bone-forming lesion that often occurs in young adults with a predilection for the lower limbs and spine. It is characterized by the formation of osteoid tissue, a precursor to bone, and can cause pain and restricted mobility in affected areas. Osteoid osteoma of the hand and fingers is rare, thus representing a diagnostic challenge. A written informed consent was provided from the patient's father for the publication and sharing all images and clinical data concerning the patient.We are reporting a case of an 11-year-old girl who presented with persistent pain and swelling in her left index finger, as well as limited mobility, over the course of 1 year. Nonsteroidal anti-inflammatory drugs eased the pain, but it resurfaced once the medication was discontinued.A series of investigations, showed a lytic lesion at the second proximal phalangeal neck, with features indicative of osteoid osteoma.Excision with bone grafting was performed as definitive therapy with pathological confirmation of the osteoid osteoma diagnosis. Nevertheless, the patient returned 2 years later with a recurrence of her previous symptoms, and further tests suggested a recurrence of osteoid osteoma. To address the recurrence, a modified open thermoablation technique was used. Thermoablation is a minimally invasive procedure that uses heat to destroy the tumor cells, and it has been shown to be effective in treating osteoid osteoma. The modified open approach involves making a small incision to access the tumor and delivering heat directly through a previously CT-guided inserted Kirschner wire to the affected area.The patient reported no pain at 1 month and 1 year after the surgery, with no radiological signs of recurrence, indicating complete excision of the lesion.Overall, this case highlights the challenges of diagnosing and treating osteoid osteoma in the hands and fingers. Further research is needed to better understand the underlying causes, potential risk factors, and optimal treatment for osteoid osteoma recurrence.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.