支气管腺瘤/纤毛黏结性乳头状肿瘤（BA/CMPT）和硬化性肺泡细胞瘤（SP）是罕见且形态独特的周围肺肿瘤，具有缓慢进展的特点。这些肿瘤之前未被描述为具有相互重叠的形态特征，并且通常在基因层面上是不同的。最近遇到了两例表现出BA/CMPT和SP之间形态特征混合的病例，并详细描述了它们的形态学和免疫表型。这两例病例都展示出典型的SP间质圆形细胞（TTF1+、EMA+），以及更具代表性的BA/CMPT区域。其中一例病例在BA/CMPT区域表达了BRAFV600E，但在类似SP的细胞中未表达。尽管这些病例可能代表了碰撞性肿瘤，或者是SP中罕见的上皮异型变化的例子，但它们也引发了这两个实体在真正混合性肿瘤中可能偶尔存在的可能性。© 作者（2023），由牛津大学出版社代表美国临床病理学学会发表。版权所有。如需授权，请发送电子邮件至：journals.permissions@oup.com。

Bronchiolar adenoma/ciliated muconodular papillary tumor (BA/CMPT) and sclerosing pneumocytoma (SP) are both rare and morphologically unique peripheral lung tumors with indolent behavior. These tumors have not been previously described as showing overlapping morphologic features and are generally genetically distinct.Two cases were recently encountered that show hybrid morphologic features between BA/CMPT and SP, and the morphology and immunophenotype are described in detail.Both cases showed interstitial round cells typical of SP (TTF1+, EMA+), as well as areas more typical of BA/CMPT. One case showed BRAFV600E expression in the BA/CMPT areas but not in the SP-like cells.Although it is possible that these cases represent collision tumors or are examples of unusual metaplastic epithelial changes in SP, they also raise the possibility that these 2 entities could occasionally coexist in true hybrid tumors.© The Author(s) 2023. Published by Oxford University Press on behalf of American Society for Clinical Pathology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.