该研究旨在评估伊朗北部戈勒斯坦省骨骼和软组织癌症的流行病学特征，时间跨度为2004年至2016年。这是一项描述性横断面研究。纳入2004年至2016年期间患有原发性骨骼和软组织癌症的所有患者。数据来自戈勒斯坦基于人口的癌症登记处(GPCR)。我们计算了年龄标准化发病率(ASRs)，并报告了每10万人年的发病率。还计算了估计的年百分比变化(EAPC)以评估这些癌症发病率的时间趋势。骨癌和软组织癌的ASRs分别为每10万人年1.33和1.43。该研究还显示，男性(1.51)的骨癌ASR高于女性(1.15)。城市人口的软组织癌ASR(1.58)高于农村(1.27)，女性(1.37)低于男性(1.49)。骨癌发病率呈现两个高峰。第一个高峰出现在10至20岁年龄组，第二个高峰出现在60岁以上患者中。研究期间骨癌(EAPC=-1.14; P>0.05)和软组织癌(EAPC=-2.73; P>0.05)的发病率未显示出显著的时间趋势。在制定癌症控制计划时，卫生政策制定者应考虑骨骼和软组织癌症的流行病学特征，包括性别、年龄和居住地。©本文作者 2023。本文为开放获取文章，根据创作人公共许可证进行分发 (https://creativecommons.org/licenses/by/4.0)，可自由使用、分发和复制，并确保原始作品得到适当引用。

This study was conducted to evaluate the epidemiological features of bone and soft cancers in the Golestan province, Northern Iran from 2004 to 2016.This is a descriptive cross-sectional study. All patients with primary bone and soft tissue cancers between 2004 and 2016 were included. Data were obtained from Golestan population-based cancer registry (GPCR). We calculated age-standardized incidence rates (ASRs) and reported the rates per 100000 person-year. Estimated annual percent change (EAPC) was also calculated to assess temporal trends in incidence rates of these cancers.The ASRs of bone cancers and soft tissue cancers were 1.33 and 1.43 per 100000 person-year, respectively. This study also showed that the ASR of bone cancer was higher in men (1.51) than women (1.15). The ASR of soft tissue cancers in the urban population (1.58) was higher than rural (1.27), and was lower in women (1.37) than men (1.49). Two peaks were seen in the incidence of bone cancer. The first peak was in the age group of 10 to 20 years and the second was in patients over 60. We did not find significant temporal trends in the incidence of bone (EAPC=-1.14; P>0.05) and soft tissue cancers (EAPC=-2.73; P>0.05) during the study period.Epidemiological features of bone and soft tissue cancers including gender, age and place of residence should be considered by health policy makers in designing cancer control programs.© 2023 The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.