上皮-肌上皮癌（EMC）是一种极为罕见的恶性唾液腺肿瘤。EMC主要影响主要唾液腺，特别是腮腺，但也会影响其他次要唾液腺。它占所有唾液腺肿瘤的0.5-1%以下。EMC的多次复发相对较少见。文献中关于多次复发的报道极为有限。以外部清晰细胞和内部导管细胞组成的两相性小管结构是其病理学鉴别特征。然而，组织学变异很常见，导致精确诊断具有挑战性。我们报告了一例在六年期间多次复发的EMC病例。版权所有©2023 Elsevier Ltd. 保留所有权利。

Epithelial-myoepithelial carcinoma (EMC) is a type of malignant salivary gland tumors that is extremely rare. EMC primarily affects major salivary glands, particularly the parotid gland, but minorsalivary glands are also affected. It contributes less than 0.5-1% of all salivary gland neoplasms. Multiple recurrences are relatively rare with EMC. There have been very few reports of multiplerecurrences in the literature. Biphasic tubular structures composed of externalclear cells and inner ductal cells are the distinguishing histopathological feature. However, histological variation is prevalent, making a precise diagnosis challenging. We present a case of EMC that had multiple recurrences during a six-year period.Copyright © 2023 Elsevier Ltd. All rights reserved.