癌症发展的单细胞特征鉴定预病状态中
Single-cell characterization of tumor evolution from precursor diseases.
发表日期：2023 Aug 04
作者：
Jiling Feng, Yu Zeng, Shengli Li
来源：
Trends in Cancer
摘要：
阐明前驱疾病的特征对于理解肿瘤发展过程中的恶性转化非常重要。在最近的一项研究中，Dang等人通过整合单细胞RNA测序（scRNA-seq）和B细胞受体测序（scBCR-seq）技术，对前驱状态到多发性骨髓瘤（MM）的细胞和分子演化进行了表征。版权所有 © 2023 Elsevier Inc. 保留所有权利。
Elucidating the characteristics of precursor diseases is important to the understanding of malignant transformation during tumor progression. In a recent study, Dang et al. characterized the cellular and molecular evolution from precursor conditions to multiple myeloma (MM) by integrating single-cell RNA sequencing (scRNA-seq) and B cell-receptor sequencing (scBCR-seq).Copyright © 2023 Elsevier Inc. All rights reserved.