多医院网络对同步结直肠肝转移患者接受切除手术或消融治疗几率差异的影响
The impact of a multi-hospital network on the inequality in odds of receiving resection or ablation for synchronous colorectal liver metastases.
发表日期:2023 Aug 07
作者:
Roos G F M van der Ven, Daan Westra, Felice N van Erning, Ignace H de Hingh, Steven W M Olde Damink, Agnes Paulus, Wouter K G Leclercq, Marcel den Dulk,
来源:
MEDICINE & SCIENCE IN SPORTS & EXERCISE
摘要:
本研究旨在调查专家医院和非专家医院中诊断的异步结直肠肝转移(SCLM)患者在切除和/或消融治疗利用上的不平等是否自从多医院网络开始以来有所改变。本研究纳入了2009年至2020年间被诊断出SCLM的患者。在网络开始运行之前(2009-2012年)、网络开始运行期(2013-2016年)和成熟网络期间(2017-2020年)分析了接受消融和/或切除的可能性。在全国范围内,2009年至2020年间共有13,981名患者被诊断出SCLM,其中1,624名患者在网络内被诊断出。在网络的专家医院中,36.7%的患者接受了消融和/或切除治疗,而在非专家医院中为28.3%(p < 0.01)。在专家医院和非专家医院被诊断出的患者中,接受消融和/或切除治疗的几率比为1.38(p = 0.581,网络之前),1.66(p = 0.108,网络开始运行期),2.48(p = 0.090,成熟网络期)。在全国范围内同样存在相同的趋势(分别为比值比1.41,p = 0.011;比值比2.23,p < 0.001;比值比3.20,p < 0.001)。在专家医院被诊断的患者比非专家医院被诊断的患者更有可能接受SCLM的消融和/或切除治疗。尽管多医院网络开始运行,但这种差异随时间的推移而增加。建立多医院网络对于减少现有的不平等就诊几率没有产生影响。专业肿瘤治疗越来越多地通过多医院网络提供。然而,对于这些网络的有效性存在着有限的经验证据。本研究分析了一个区域多医院网络是否能够改善接受专业肿瘤治疗的平等机会。
This study investigates whether inequalities in the utilization of resection and/or ablation for synchronous colorectal liver metastases (SCLM) between patients diagnosed in expert and non-expert hospitals changed since a multi-hospital network started.Patients diagnosed with SCLM between 2009 and 2020 were included. The likelihood of receiving ablation and/or resection was analyzed in the prenetwork (2009-2012), startup (2013-2016), and matured-network (2017-2020) periods.Nationwide, 13.981patients were diagnosed between 2009 and 2020, of whom 1.624 were diagnosed in the network. Of patients diagnosed in the network's expert hospitals, 36.7% received ablation and/or resection versus 28.3% in nonexpert hospitals (p < 0.01). The odds ratio (OR) of receiving ablation and/or resection for patients diagnosed in expert versus nonexpert hospitals increased from 1.38 (p = 0.581, pre-network), to 1.66 (p = 0.108, startup), to 2.48 (p = 0.090, matured-network). Nationwide, the same trend occurred (respectively OR 1.41, p = 0.011; OR 2.23, p < 0.001; OR 3.20, p < 0.001).Patients diagnosed in expert hospitals were more likely to receive ablation and/or resection for SCLM than patients diagnosed in non-expert hospitals. This difference increased over time despite the startup of a multi-hospital network. Establishing a multi-hospital network did not have an effect on reducing the existing unequal odds of receiving specialized treatment.Specialized oncology treatments are increasingly provided through multi-hospital networks. However, scant empirical evidence on the effectiveness of these networks exists. This study analyzes whether a regional multi-hospital network was able to improve equal access to specialized oncology treatments.