乳腺癌整形手术（oncoplastic breast surgery, OBS）结合了整形外科技术和传统的保乳手术（breast-conserving surgery, BCS），扩大了BCS的适用范围。目前关于OBS后患者自我报告结果(patient-reported outcomes, PROs) 的数据较少。这里我们使用BREAST-Q比较OBS和BCS后的长期PROs。我们筛选了2006年至2019年间接受OBS或BCS的妇女，她们在手术后3至5年内完成了至少一个长期BREAST-Q调查表。比较了接受OBS/BCS的妇女的基线特征。使用1：2的倾向性匹配方法将接受OBS的妇女与接受BCS的妇女配对（根据年龄、体重指数、种族、T期和多发性）。比较了术前和术后3至5年的BREAST-Q评分。共纳入297名患者进行分析（99 OBS / 198 BCS）。接受OBS的妇女年龄较小（p < 0.001），BMI较高（p = 0.005），多发性疾病发病率较高（p = 0.004）。两组在淋巴结分期、重新切除率、腋窝手术、化疗、内分泌治疗或放疗方面没有差异。在术前进行倾向性匹配后，接受OBS的妇女在心理社会福祉方面报告较低（63对比100，p = 0.039），但与接受BCS的妇女相比，乳房满意度和性福感相似；然而，只有3名接受BCS的患者的术前BREAST-Q评分可供回顾。在长期随访中，接受OBS的妇女在术后4年报告较低的心理社会得分（74对比93, p = 0.011），但在术后5年（76对比77， p = 0.83），差异不再存在。在长期乳房满意度和性福感方面没有差异。接受OBS的妇女疾病负担较重，可能代表了非传统BCS候选人群；她们在长期乳房满意度和性福感方面与接受BCS的妇女相似。虽然接受OBS的妇女术前和随访期间心理社会福祉得分较低，但在术后5年不再存在这种差异。 © 2023. 外科肿瘤学会。

Oncoplastic breast surgery (OBS) combines plastic surgery techniques with conventional breast-conserving surgery (BCS) and expands BCS eligibility. Limited data are available on patient-reported outcomes (PROs) after OBS. Here we compare long-term PROs after OBS and BCS utilizing the BREAST-Q.Women undergoing OBS or BCS between 2006 and 2019 who completed ≥ 1 long-term BREAST-Q survey 3-5 years postoperatively were identified. Baseline characteristics were compared between women who underwent OBS/BCS. Women who underwent OBS were paired with those who underwent BCS using 1:2 propensity matching [by age, body mass index (BMI), race, T stage, and multifocality]. BREAST-Q scores were compared preoperatively and 3-5 years postoperatively.A total of 297 patients were included for analysis (99 OBS/198 BCS). Women who underwent OBS were younger (p < 0.001) and had higher BMI (p = 0.005) and multifocal disease incidence (p = 0.004). There was no difference between groups in nodal stage, re-excision rates, axillary surgery, chemotherapy, endocrine therapy, or radiotherapy. After propensity matching preoperatively, women who underwent OBS reported lower psychosocial well-being (63 versus 100, p = 0.039) but similar breast satisfaction and sexual well-being compared with women who underwent BCS; however, only three patients who underwent BCS had preoperative BREAST-Q scores available for review. In long-term follow-up, women who underwent OBS reported lower psychosocial scores (74 versus 93, p = 0.011) 4 years postoperatively, but not at 5 years (76 versus 77, p = 0.83). There was no difference in long-term breast satisfaction or sexual well-being.Women who undergo OBS present with a larger disease burden and may represent a group of non-traditional BCS candidates; they reported similar long-term breast satisfaction and sexual well-being compared with women who undergo BCS. While women who underwent OBS reported lower psychosocial well-being scores preoperatively and during a portion of the follow-up period, this difference was no longer seen at 5 years postoperatively.© 2023. Society of Surgical Oncology.