《经腹腔镜超声引导下应用荧光ICG阳性染色的解剖性Ⅷ段肝切除术》
Laparoscopic Anatomical Liver Resection of Segment VIII by Using ICG Fluorescence Positive Staining Under the Guidance of Laparoscopic Ultrasonography.
发表日期:2023 Aug 09
作者:
Ji Sun, Zhi-Yu Lu, Jian-Xin Zhai, Meng-Ran Lang, Hong-Guang Wang
来源:
ANNALS OF SURGICAL ONCOLOGY
摘要:
解剖学切缘切除术是一种完全切除第三级门脉分支(LAM)领域的手术程序(Wakabayashi et al. in J Hepatobil Pancreat Sci 29(1):82-98, 2022. https://doi.org/10.1002/jhbp.899)。 S8的腹腔镜分节切除术因精确解剖S8 Glissonean导管及中右两个肝静脉的曝光而被认为具有技术挑战性(Ome et al. in J Am Coll Surg 230(3):e13-e20, 2020; Wakabayashi等在Ann Surg 261(4):619-29,2015年. https://doi.org/10.1097/sla.0000000000001184;Monden et al. in J Hepatobil Pancreat Sci 29(1):66-81, 2022年,https://doi.org/10.1002/jhbp.898)。本报告描述了一种新的方法,可以减少对正常组织的不良损伤和并发症。一名53岁男性因患有乙型肝炎10年而入院治疗位于VIII段内的两个结节性肿瘤。手术程序以经皮穿刺注射5 mL、0.025 mg/mL结合绿素(ICG)到S8门脉分支,通过腹腔镜超声引导下使用18G PTCD针(Xu et al. in Surg Endosc 34(10):4683-4691, 2020. https://doi.org/10.1007/s00464-020-07691-5; Wang et al. in Ann Surg 274(1):97-106, 2021. https://doi.org/10.1097/sla.0000000000004718;Aoki et al. in J Am Coll Surg 230(3):e7-e12, 2020. https://doi.org/10.1016/j.jamcollsurg.2019.11.004) ,然后在肝脏的颅侧进行肝切割,利用ICG荧光图像暴露中右肝静脉的根部,解剖和结扎S8门脉导管。切除标本送往病理组织学诊断。手术耗时200分钟,全普林格操作耗时60分钟。预计失血量为110毫升。两个结节的最终病理学结果是肝细胞癌(HCC)。患者于术后第6天无并发症出院。腹腔镜解剖学区段切除S8的可行性已得到证实。在腹腔镜超声引导下,ICG阳性染色被证明是解剖学切缘切除的最佳选择。(© 2023该作者(们))。
Anatomical segmentectomy is a surgical procedure that completely removes a territory (or territories) of the third-order portal venous branches of a Couinaud segment (Wakabayashi et al. in J Hepatobil Pancreat Sci 29(1):82-98, 2022. https://doi.org/10.1002/jhbp.899 ). Laparoscopic segmentectomy of S8 is considered technically challenging because of the Precise dissection of the Glissonean pedicle of S8, and exposure of the middle and right hepatic veins are required (Ome et al. in J Am Coll Surg 230(3):e13-e20, 2020; Wakabayashi et al. in Ann Surg 261(4):619-29, 2015. https://doi.org/10.1097/sla.0000000000001184 ; Monden et al. in J Hepatobil Pancreat Sci 29(1):66-81, 2022. https://doi.org/10.1002/jhbp.898 ). This report describes a new approach, which can reduce unwanted damage to normal tissues and complications.A 53-year-old man who has suffered from hepatitis B for 10 years was admitted for the treatment of two nodular tumors located in segment VIII. The surgical procedure began with the percutaneous injection of 5 mL, 0.025 mg/mL of ICG into the S8 portal branch by using an 18G PTCD needle under the guidance of laparoscopic ultrasound (Xu et al. in Surg Endosc 34(10):4683-4691, 2020. https://doi.org/10.1007/s00464-020-07691-5 ; Wang et al. in Ann Surg 274(1):97-106, 2021. https://doi.org/10.1097/sla.0000000000004718 ; Aoki et al. in J Am Coll Surg 230(3):e7-e12, 2020. https://doi.org/10.1016/j.jamcollsurg.2019.11.004 ), followed by liver transection on the cranial side of the liver, which used the ICG fluorescence images for exposing the roots of the middle and right hepatic veins and dissecting and ligating S8 portal pedicle. The excision specimen was sent for histopathological diagnosis.It took 200 min for the operation and 60 min for the total Pringle maneuver. The estimate of blood loss was 110 mL. The final histopathologic results of the two nodules were hepatocellular carcinoma (HCC). The patient was discharged on postoperative Day 6 with no complications.Laparoscopic anatomical liver resection of S8 has been demonstrated to be feasible. Under the guidance of laparoscopic ultrasonography, ICG positive staining was proven to be optimal for Anatomical segmentectomy.© 2023. The Author(s).