眼部转移灶的后节表现。
Posterior segment manifestations of ocular metastasis.
发表日期:2023 Aug 10
作者:
Wijak Kongwattananon, Thananop Pothikamjorn, Thanapong Somkijrungroj
来源:
CURRENT OPINION IN OPHTHALMOLOGY
摘要:
本文回顾并总结了近期关于眼部转移癌后部表现的眼部成像发现和治疗的已发表数据。进步的眼部成像技术可以帮助区分眼部转移癌与其他类似病变,包括原发性眼内肿瘤或感染。近期的病例报告表明,有针对性的全身治疗成功地实现了玻璃体和脉络膜转移癌的局部控制。转移可导致多种不同的后部眼部表现。脉络膜是最常见的转移部位,而转移到视网膜和视盘的肿瘤则很少见。建议对可能存在转移性眼部疾病的患者进行广泛的调查,以确定潜在的原发癌和全身性转移。目前,尚无关于治疗策略的共识。治疗通常包括全身化疗联合局部治疗,如放疗、激光治疗或抗血管内皮生长因子(抗VEGF)治疗。版权所有© 2023 Wolters Kluwer Health, Inc. 保留所有权利。
This article reviewed and summarized recent published data on ocular imaging findings and treatment of posterior segment manifestations of ocular metastasis.Advanced ocular imaging can help differentiate ocular metastases from other mimicking lesions, including primary intraocular tumors or infections. Recently, case reports have demonstrated the successful use of targeted systemic therapy to achieve local control of vitreous and choroidal metastases.Metastasis can lead to a wide variety of posterior segment ocular manifestations. The choroid is the most common metastatic site, whereas tumor metastasizing to the retina and optic disc are rare. Patients with possible metastatic eye disease are recommended to undergo extensive investigation to determine the underlying primary cancer and ongoing systemic metastases. Currently, there is no consensus on the treatment strategy. Treatment generally includes systemic chemotherapy in combination with local treatment, such as radiotherapy, laser therapy, or anti-vascular endothelial growth factor (anti-VEGF) treatment.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.