研究动态
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2008年至2012年间,哥斯达黎加女性患有浸润性乳腺癌的群体级描述首次出现:一项横断面研究。

The First Population-Level Description of Women Diagnosed With Invasive Breast Cancer in Costa Rica From 2008 to 2012: A Cross-Sectional Study.

发表日期:2023
作者: Amada Aparicio, Percy Guzman, Melvin Morera, Yoleni Calvo, Marjorie Obando, Denis Landaverde, Ileana González, Esmeralda Ramirez-Pena
来源: Bone & Joint Journal

摘要:

乳腺癌是全球妇女乳腺相关死亡的主要原因。在哥斯达黎加,它在发病率方面居首位,在死亡率方面排名第四。然而,在哥斯达黎加,缺乏关于乳腺癌患者治疗模式和结果的全面信息。本研究利用了国家肿瘤登记处的数据,该数据与哥斯达黎加社会保障基金(CCSS)合并,以确保综合获取临床信息。该研究是前瞻性的,重点针对2008年1月至2012年12月间被诊断为乳腺癌的患者。这个联合数据集允许对哥斯达黎加乳腺癌患者的患者特征、治疗模式和结果进行更全面的分析。 在此期间被诊断出来的4775名患者中,有3160名符合我们研究的纳入标准。平均诊断年龄为59.1岁,32.5%的患者年龄超过65岁。大多数患者(55.4%)自称是家庭主妇,46.5%的患者进行了核心针活检诊断。约60%的妇女被诊断为早期疾病(IA、IIA和IIB),而1.7%的人患有转移性疾病,主要影响骨骼。诊断至手术之间的平均时间间隔为72天。大多数患者(88.7%)接受手术作为初步治疗,超过一半(54.4%)接受了某种辅助治疗。此外,85.6%的患者完成了他们的预定治疗。 本研究对哥斯达黎加乳腺癌患者的特征和治疗模式提供了全面而详细的描述。研究结果有助于加深我们对这一人群乳腺癌的了解,并为进一步的研究和改进乳腺癌管理和护理提供了基础。
Breast cancer is the leading cause of cancer-related deaths among women worldwide. In Costa Rica, it ranks first in incidence and fourth in terms of mortality. However, there is a lack of comprehensive information on treatment patterns and outcomes for breast cancer patients in Costa Rica.This study utilized data from the National Tumor Registry, which was merged with the Costa Rica Social Security Fund (CCSS) to ensure comprehensive access to clinical information. The study is prospective and focused on patients diagnosed with breast cancer between January 2008 and December 2012. This combined dataset allowed for a more comprehensive analysis of patient characteristics, treatment patterns, and outcomes related to breast cancer in Costa Rica.Among the 4775 patients diagnosed during this period, 3160 met the inclusion criteria for our study. The average age at diagnosis was 59.1 years, with 32.5% of patients being over the age of 65. Most of the patients (55.4%) identified themselves as homemakers, while 46.5% underwent core needle biopsy for diagnosis. Approximately 60% of women were diagnosed with early-stage disease (IA, IIA, and IIB), while 1.7% had metastatic disease, mainly affecting the bone. The mean interval between diagnosis and surgery was 72 days. Most patients (88.7%) received surgery as their initial treatment, and over half (54.4%) received some form of adjuvant therapy. Additionally, 85.6% of patients completed their prescribed treatment.This study provides a comprehensive and detailed description of the characteristics and treatment patterns among breast cancer patients in Costa Rica. The findings contribute to our understanding of the disease in this population and can serve as a foundation for further research and improvement in breast cancer management and care.