放疗（RT）的大约一半是以姑息治疗为目的。姑息放疗的临床研究旨在处理症状，改善生活质量（QoL），评估支持性护理，并确定最佳的剂量分段计划。我们的目的是描述在加拿大放射肿瘤学协会（CARO）年度科学会议（ASM）上姑息放疗研究的患病率，以往的已发表的工作中评估了1992-2002年的情况进行对比。两位作者独立地回顾了发表的摘要（2003-2021年），并将每个摘要分类为治愈性意图、姑息性意图、两者兼而有之或都不是。如果摘要描述了不可治愈的恶性肿瘤以及主要用于症状控制或生活质量的干预措施，则被认为是姑息性的。记录了研究类型、治疗的主要部位和舒缓的症状。进行了描述性和总结性统计，包括一元方差分析趋势检验。4566个摘要中有339个被分类为姑息性（百分比为7.4%，每年范围为2.4%至13.9%）。其中7.7%（26/339）描述了I-III期试验。主要的原发部位是肺部（39/339），最常见的转移部位是骨骼（34.2%）。分别报告了31.6%（107/339）的生活质量、37.8%（128/339）的症状和17.7%（60/339）的毒副反应结果。最常研究的症状是疼痛（38/339）。摘要被分类为治愈性、姑息性或报告毒副反应终点的比例随时间的推移而发生了显著变化（所有p<0.0001）。尽管姑息主题的摘要比例随着时间的推移而增加，但在达到与临床实践中姑息放疗的患病率相当之前，仍存在显着差距。©2023年。该作者（Author(s)）在Springer-Verlag GmbH Germany 安全之下，作为Springer Nature的一部分，进行独家许可。

Approximately half of all radiotherapy (RT) is delivered with palliative intent. Clinical research in palliative RT aims to manage symptoms, improve quality of life (QoL), evaluate supportive care, and determine optimal dose-fractionation schedules. Our aim was to describe the prevalence of palliative research at the Canadian Association of Radiation Oncology (CARO) Annual Scientific Meeting (ASM) over time and compare this analysis to previously published work which evaluated the years 1992-2002.Published abstracts (2003-2021) were independently reviewed by two authors who categorized each as curative-intent; palliative-intent; pertaining to both populations; or neither. Abstracts were considered palliative if they described incurable malignancy and interventions primarily for symptom control or QoL. Type of study, primary, site treated, and symptoms palliated were recorded. Descriptive and summary statistics were calculated including one-way ANOVA test for trend.Three hundred thirty-nine out of 4566 abstracts (7.4%, range 2.4-13.9% per year) were classified as palliative. 7.7% (26/339) described phase I-III trials. The main primary site was the lung (39/339) and the most common metastatic site was the bone (34.2%). QoL, symptom and toxicity outcomes were reported in 31.6% (107/339), 37.8% (128/339) and 17.7% (60/339), respectively. The most common symptom investigated was pain (38/339). The proportion of abstracts classified as curative, palliative or reporting toxicity endpoints demonstrated significant change over time (all p<0.0001).While proportion of palliative themed abstracts has increased with time, there remains a significant gap before equivalence with the prevalence of palliative RT in clinical practice is achieved.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.