前列腺特异性膜抗原正电子发射断层扫描 (PET) 对晚期肾细胞癌管理的强化或减弱的临床影响。
Clinical impact of Prostate-Specific Membrane Antigen Positron Emission Tomography (PET) on intensification or deintensification of advanced renal cell carcinoma management.
发表日期：2023 Aug 18
作者：
Shivanshan Pathmanathan, Arsalan Tariq, Adam Pearce, Handoo Rhee, Samuel Kyle, Sheliyan Raveenthiran, David Wong, Rhiannon McBean, Phillip Marsh, Steven Goodman, Nattakorn Dhiantravan, Rachel Esler, Nigel Dunglison, Anojan Navaratnam, John Yaxley, Paul Thomas, David A Pattison, Jeffrey C Goh, Chun Loo Gan, Matthew J Roberts
来源：
Eur J Nucl Med Mol I
摘要：
前列腺特异膜抗原(PSMA)正电子发射断层显像（PET）在肾细胞癌中有新兴的应用。在此，我们报告了在复发性或转移性肾细胞癌（RCC）中使用PSMA PET的经验。对2015年至2020年期间在三个医疗机构接受PSMA PET诊断可疑复发性或原发性转移性RCC的所有患者进行了回顾性分析。主要结果是PSMA PET扫描后处理方式的变化（强化或减弱）。次要结果包括PSMA亲和性部位的组织病理学对应性，比较PSMA PET和诊断性CT上的疾病部位以及系统治疗的时间。© 2023. 作者。
There is an emerging role of the use of Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) in renal cell carcinoma. Herein, we report our experience in use of PSMA PET in recurrent or metastatic renal cell carcinoma (RCC).A retrospective analysis of all patients who underwent PSMA PET for suspected recurrent or de-novo metastatic RCC between 2015 and 2020 at three institutions was performed. The primary outcome was change in management (intensification or de-intensification) following PSMA PET scan. Secondary outcomes included histopathological correlation of PSMA avid sites, comparison of sites of disease on PSMA PET to diagnostic CT and time to systemic treatment.© 2023. The Author(s).