大气中的重金属（HMs）在海洋鱼类中的生物积累是一个日益严重的全球性问题，可能对人类健康产生潜在风险。本研究分析了2018年4月至2019年2月在受污染的德班盆地和原始的维达尔角所捕捞到的成年雄性和雌性赤鞭鯖和矶鲷鱼的肌肉组织、鳃和肠道中的HMs。结果表明HMs水平存在种间、空间和器官特异性的变异。在德班盆地，矶鲷鱼的As（2.3±0.2）mg/kg，Cr（2.6±0.2）mg/kg， Ni（2.0±0.1）mg/kg和Pb（4.1±0.3）mg/kg的生物积累超过了世界卫生组织（WHO）的规定限值。赤鞭鯖的Ni（1.6±0.2）mg/kg，Pb（4.7±0.6）mg/kg和Zn（52±3.01）mg/kg也超过了WHO的规定限值。对于两个物种的肌肉来说，德班盆地的金属污染指数（MPI）值（>5.13）高于维达尔角（<3.32）。矶鲷鱼的肝脏和鳃以及赤鞭鯖的肠道表现出与环境浓度成比例的较高HMs积累模式，说明这两个物种具有HMs污染的生物指示潜力。风险评估表明，两种鱼类的铬（Cr）目标危害指数>1，铅（Pb）目标癌症风险<10-4，表明从德班盆地的鱼类摄入可能存在重要的非致癌和致癌健康风险。本研究建议针对矶鲷鱼的日常摄入限量为16克/天，赤鞭鯖为14克/天，以确保健康安全。这些发现有助于了解德班盆地的HMs污染，并为决策者和政策制定者提供重要信息，以制定有效的策略来缓解和管理鱼类群体中的HMs污染。©2023年。作者（们）。

The bioaccumulation of heavy metals (HMs) in marine fish is a growing global concern due to potential human health risks. The study analyzed HM in the muscle tissue, gills, and gut of adult male and female cape horse mackerel and slinger seabream caught in the polluted Durban Basin and pristine Cape Vidal from April 2018 to February 2019. Results revealed interspecific, spatial, and organ-specific variability in HM levels. In the Durban Basin, slinger seabream had bioaccumulation (in mg/kg) of As (2.3 ± 0.2), Cr (2.6 ± 0.2), Ni (2.0 ± 0.1), and Pb (4.1 ± 0.3) while cape horse mackerel had Ni (1.6 ± 0.2), Pb (4.7 ± 0.6), and Zn (52 ± 3.01) exceeding World Health Organization (WHO) regulatory limits. Metal pollution index (MPI) values were also higher in Durban Basin (> 5.13) than Cape Vidal (< 3.32) for both species' muscles. Liver and gills of slinger seabream and gut of cape horse mackerel exhibited higher HM accumulation patterns proportionate to the environmental concentrations, indicating the bioindicative potential of HM pollution by the two species. Risk assessment indicated that both fish species had target hazard quotient > 1 for Cr, and target cancer risk < 10-4 for Pb, implying significant potential non-carcinogenic and carcinogenic health risks associated with fish consumption from the Durban Basin. The study recommends daily consumption limits of 16 g/day for slinger seabream and 14 g/day for cape horse mackerel to ensure health safety. The findings contribute to the understanding of HM pollution in the Durban Basin and provide important information for decision-makers and policymakers in developing effective strategies to mitigate and manage HM contamination in fish populations.© 2023. The Author(s).