英国和爱尔兰共和国的非黑色素瘤皮肤癌发病率:一项系统综述。
The incidence of non-melanoma skin cancer in the UK and the Republic of Ireland: a systematic review.
发表日期:2023 Jun 01
作者:
Nader Ibrahim, Stephen R Ali, Thomas D Dobbs, A G John Gibson, Hayley A Hutchings, S Iain Whitaker
来源:
Burns & Trauma
摘要:
基底细胞癌(BCC)和皮肤鳞状细胞癌(cSCC)仍然是最常见的恶性肿瘤,对癌症登记点的工作量贡献超过所有癌症的总和。皮肤癌的特性以及登记点目前采用的编码方法使工作量的表现出偏差。设计了一项全面搜寻英国和爱尔兰地区或国家水平的BCC和/或cSCC发病率的研究。标准化方法被分组以进行比较,并采用了偏倚评估工具。汇编了英国和爱尔兰的16项流行病学研究,对BCC/cSCC在48年期间的发病率、趋势和新兴危险因素进行了分析。英国的BCC发病率每年增长高达4%,而威尔士的BCC和cSCC发病率分别每年增长6.6%和1.6%。BCC/cSCC与社会贫困之间存在反向关系。尽管老年人仍然是风险最高的人群,但30-49岁的人群的增长率约为4%。本综述介绍了英国发病率的增加情况,其中威尔士、东南部、西部和中部地区的发病率较高。发病率在社会贫困程度较低的人群中更高,并发现年龄较小的人群中发病率逐渐增加,但需要进一步的趋势分析。登记点内需要更全面的数据收集方法,以确保准确的表现和流动的比较。必须实施服务规划和公众意识宣传活动,以防止未来服务的过载。
Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC) remain the most prevalent malignancies, contributing a higher workload to cancer registries than all cancers combined. The nature of skin cancers in addition to current coding methods employed by registries give a skewed representation of the workload.A comprehensive search examining the incidence of BCC and/or cSCC at a regional or national level in the UK and Ireland was devised. Standardisation methods were grouped to permit comparison, and a bias assessment tool was employed.Sixteen UK and Republic of Ireland epidemiological studies on BCC/cSCC over a 48-year period were compiled, examining incidence, trends and emerging risk factors.Incidence of BCC within the UK is increasing annually by up to 4%, with rates in Wales increasing by up to 6.6% and 1.6% annually for BCC and cSCC, respectively. Inverse relationships are noted between BCC/cSCC and social deprivation. Although the elderly remain the most at risk, the 30-49 age group have illustrated growth rates of approximately 4%.This review outlines increasing incidence in the UK with higher rates noted in Wales, the Southeast, West and Central regions. Incidence rates are higher amongst the least socially deprived and an increasing incidence amongst younger age groups was found, however further trend analysis is required. A more comprehensive data collection method within registries is necessary to ensure accurate representation and fluid comparison. Service planning and public awareness campaigns must be implemented to prevent overwhelming future services.