揭示癌症中转录异质性的景观。
Deciphering the landscape of transcriptional heterogeneity across cancer.
发表日期：2023 Aug 03
作者：
Thomas P Jones, Nicholas McGranahan
来源：
CANCER CELL
摘要：
通过整合77项研究和24种癌症类型的单细胞RNA测序数据集，Gavish等人揭示了基因表达的重复模式，这些模式解释了肿瘤中观察到的转录组异质性的显著比例，并探讨了它们的功能重要性。版权所有 © 2023 Elsevier Inc. 保留所有权利。
By integrating scRNA-seq datasets across 77 studies and 24 cancer types Gavish et al. uncover recurrent patterns of gene expression that explain a significant proportion of transcriptomic heterogeneity observed in cancer and explore their functional significance.Copyright © 2023 Elsevier Inc. All rights reserved.