本案报告的原因是一个已经有多发性骨髓瘤病史的患者体内存在大量浆母细胞。流式细胞术是诊断血液恶性肿瘤的"黄金标准"技术。这种技术适用于所有液体，并且在疑似血液恶性肿瘤的情况下，应该在胸腔积液、心包积液和腹水等液体中进行。如果无法进行流式细胞术检测，还可以使用合适的标记物进行免疫组织化学检测。该案例揭示了浆母细胞对胸腔的浸润。骨髓瘤细胞通过免疫细胞化学和流式细胞术进行了表征。© 2023作者。由约翰·威利·萨姆斯有限公司出版的细胞病理学杂志发表。

This case was presented because of the number of plasmablasts in a patient with a medical history of multiple myeloma. Flow cytometry is a "gold standard" technique for the diagnosis of haematological malignancies. This technique works for all fluids and should be performed in effusions (pleural, pericardial, ascites) in cases of suspected haematological malignancy. Alternatively, immunohistochemistry using appropriate markers could be performed if flow cytometry is not available. This case illustrates a pleural infiltration by plasmablasts. Myelomatous cells were characterised by immunocytochemistry and flow cytometry.© 2023 The Authors. Cytopathology published by John Wiley & Sons Ltd.