全球变暖无疑是农业生产面临的严重挑战，特别是在热带气候下的家禽生产，这使动物处于热应激条件下，引发多种生理变化。我们进行了一项调查，以确定草药补充剂对暴露于热应激的肉鸡的脂肪激素、促炎细胞因子和代谢激素的作用。在尼日利亚南部炎热不适的食物高峰期间，将200只一日龄的肉鸡随机分配到标准饲料中，即不含叶子饲料的饲料1（T1），含5%辣木叶饲料的饲料2（T2），含5%样草饲料的饲料3（T3）和含5%槲寄生饲料的饲料4（T4），进行为期49天的饲养试验，并使用标准方法评估激素、脂肪激素和细胞因子。结果显示，与基础饲料上的鸟比较，给予样草和槲寄生饲料的鸟的三碘甲状腺原氨酸显著（p < 0.05）增加，而给予槲寄生和样草饲料的鸟的皮质酮显著（p < 0.05）降低。给予辣木叶补充剂的鸟的热休克蛋白显著（p < 0.05）降低，而给予基础饲料的鸟的脂联素在统计上（p < 0.05）高于其他处理。与基础饲料上的鸟相比，给予样草和槲寄生补充剂的鸟的白细胞介素6在统计上（p > 0.05）与基础饲料上的鸟无显著差异。与基础饲料上的鸟相比，给予样草补充剂的鸟的白细胞介素1β显著（p < 0.05）降低，而给予槲寄生补充剂的鸟的白细胞介素1β的显著最低值表现。与基础饲料上的鸟相比，给予槲寄生和样草补充剂的鸟的肿瘤坏死因子α显著（p < 0.05）增加，而给予辣木叶补充剂的鸟的肿瘤坏死因子α的显著最低值表现。总之，三种草药补充剂可降低受热应激的肉鸡的HSP 70、瘦素和脂联素，并且辣木叶补充剂可以降低热应激鸟类的促炎细胞因子表达。版权所有© 2023 Elsevier Ltd. 保留所有权利。

Global warming undoubtedly is a serious challenge facing poultry production especially in tropical climate, which subject animals to heat-stressed conditions leading to multiple physiological alterations. An investigation was conducted to determine the role of herbal supplements on adipokines, pro-inflammatory cytokines and metabolic hormones of broilers exposed to heat stress. 200 a day-old broiler chicks were randomly allotted to standard diets; diet 1 without leaf meal (T1), diet 2 with 5% Moringa oleifera (T2), diet 3 with 5% Phyllanthus amarus (T3) and diet 4 with 5% mistletoe; Viscum album (T4) in a 49-day feed trial during the peak of thermal discomfort in Southern Nigeria, to assess hormones, adipokines and cytokines using standard procedures. Results obtained shows that triiodothyronine of birds fed phyllanthus and mistletoe were significantly (p < 0.05) higher than birds on basal diet. Corticosterone of birds fed mistletoe and phyllanthus were significantly (p < 0.05) lower than those obtained in birds on basal diet. Heat shock protein of birds fed on moringa supplements were significantly (p < 0.05) lower than those in birds on basal diet. The adiponectin of birds fed on basal diet were statistically (p < 0.05) higher than other treatments. Interleukin 6 of birds on phyllanthus and mistletoe supplements were not significantly (p > 0.05) different from birds on basal diet. Interleukin 1β of birds fed basal diet was significantly (p < 0.05) higher than birds fed moringa supplements and the significantly (p < 0.05) least values obtained in those of birds fed phyllanthus supplement. Tumor necrosis factor α of birds fed on phyllanthus and mistletoe were significantly (p < 0.05) higher than birds fed basal diet and the significantly (p < 0.05) least values were obtained in birds fed moringa supplement. In conclusion, three herbal supplements decreased the HSP 70, leptin and adiponectin of broilers exposed to heat stress and moringa supplements lower pro-inflammatory cytokine expression in heat stress birds.Copyright © 2023 Elsevier Ltd. All rights reserved.