热裂解是一种依赖于半胱天冬酶通路的程序性细胞死亡，与凋亡和坏死不同。最近的研究表明，热裂解参与了许多疾病的病理过程，如癌症、动脉粥样硬化、糖尿病肾病和血液疾病。然而，热裂解参与造血恶性肿瘤发生和发展的具体机制仍需要进一步探索。本文对热裂解的特点、促进或抑制热裂解的调节机制进行了综述，并讨论了热裂解在造血恶性肿瘤中的作用，为未来临床治疗这类肿瘤提供了思路。© 2023年，作者。

Pyroptosis is a kind of programmed cell death dependent on the caspase pathway that is different from apoptosis and necrosis. Recent studies have shown that pyroptosis can be involved in the pathological processes of many diseases, such as cancers, atherosclerosis, diabetic nephropathy, and blood diseases. However, the specific mechanisms by which pyroptosis participates in the occurrence and development of hematological malignant tumors still need further exploration. This article reviews the characteristics of pyroptosis and the regulatory mechanisms promoting or inhibiting pyroptosis and discusses the role of pyroptosis in hematological malignant tumors, which could provide ideas for the clinical treatment of such tumors in the future.© 2023. The Author(s).